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. 1980 Dec 1;191(3):855–858. doi: 10.1042/bj1910855

Immobilization of DNA for affinity chromatography and drug-binding studies.

A J Macdougall, J R Brown, T W Plumbridge
PMCID: PMC1162286  PMID: 7283977

Abstract

A method is described in which double-stranded DNA is alkylated with 4-bis-(2-chloroethyl)amino-L-phenylalanine and the product immobilized on an insoluble support via the primary amino group of the phenylalanine moiety. The DNA is hence irreversibly bound to the matrix by both strands at a limited number of points.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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