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. 1981 Feb 1;193(2):401–406. doi: 10.1042/bj1930401

Studies of pyruvate-water isotope exchange catalysed by erythrocytes and proteins.

R J Simpson, K M Brindle, F F Brown, I D Campbell, D L Foxall
PMCID: PMC1162619  PMID: 7305939

Abstract

Erythrocyte suspensions in buffer made with 2H2O catalyse the exchange of pyruvate protons. This process can be easly observed by spin-echo proton magnetic resonance. The dominant exchange process is shown to be due to the formation of Schiff-base links between pyruvate and amino groups of haemoglobin. Other proteins with free alpha-amino groups also catalyse the exchange. The pH*-dependence of the exchange rate due to hen-egg-white-lysozyme reflects the dissociation of the alpha-amino group.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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