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. 1976 Aug 15;158(2):485–488. doi: 10.1042/bj1580485

Inhibition of polyamine accumulation and deoxyribonucleic acid synthesis in regenerating rat liver.

H Pösö, J Jänne
PMCID: PMC1163993  PMID: 985441

Abstract

Repeated injections of 1,3-diaminopropane into rats after partial hepatectomy caused a repression-type inhibiton of liver ornithine decarboxylase (EC 4.1.1.17) and totally prevented the marked increases in liver putrescine and spermidine concentrations that normally occur in response to partial hepatectomy. The inhibition of polyamine synthesis by diaminopropane was accompanied by a profound decrease (about 80%) in the synthesis of DNA in the regenerating rat liver without any changes in the synthesis of RNA and total liver protein.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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