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. 1977 Apr 15;164(1):287–288. doi: 10.1042/bj1640287

Net activity of phospholipase A2 in brain and the lack of stimulation of the phospholipase A2-acylation stem.

C E Rowe
PMCID: PMC1164788  PMID: 195582

Abstract

Certain observations reported previously from this laboratory have not proved reproducible. These are (1) the relatively rapid hydrolysis of added phosphatidylcholine by phospholipase A2 of tissue from the cerebral cortex of the guinea pig and (2) the stimulation by 10 micron-noradrenaline and by 1.0nM-cyclic AMP of the phospholipase A2-acylation system of isolated synaptic membranes.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Goerke J., de Gier J., Bonsen P. P. Silica gel stimulates the hydrolysis of lecithin by phospholipase A. Biochim Biophys Acta. 1971 Nov 5;248(2):245–253. doi: 10.1016/0005-2760(71)90012-9. [DOI] [PubMed] [Google Scholar]
  2. Gullis R. J., Rowe C. E. Pharmacological studies on the stimulation of the phospholipase A2-acylation system of synaptic membranes of brain, by neurotransmitters and other agonists. J Neurochem. 1976 Jun;26(6):1217–1230. doi: 10.1111/j.1471-4159.1976.tb07010.x. [DOI] [PubMed] [Google Scholar]
  3. Gullis R. J., Rowe C. E. Stimulation of phospholipase A2 of synaptosomes of guinea-pig brain by noradrenaline and other amines. Biochem Soc Trans. 1973 Jul;1(4):849–849. doi: 10.1042/bst0010849. [DOI] [PubMed] [Google Scholar]
  4. Gullis R. J., Rowe C. E. The effects of noradrenaline, acetylcholine, cyclic AMP, cyclic GMP, and other agents on the concentration of unesterified fatty acids in synaptosomes and synaptic membranes. FEBS Lett. 1976 Sep 1;67(3):256–259. doi: 10.1016/0014-5793(76)80541-8. [DOI] [PubMed] [Google Scholar]
  5. Gullis R. J., Rowe C. E. The effects of noradrenaline, acetylcholine, cyclic AMP, cyclic GMP, and other agents on the concentration of unesterified fatty acids in synaptosomes and synaptic membranes. FEBS Lett. 1976 Sep 1;67(3):256–259. doi: 10.1016/0014-5793(76)80541-8. [DOI] [PubMed] [Google Scholar]
  6. Gullis R. J., Rowe C. E. The stimulation by synaptic transmitters of the incorporation of oleate into the phospholipid of synaptic membranes. Biochem J. 1975 Jun;148(3):557–565. doi: 10.1042/bj1480557. [DOI] [PMC free article] [PubMed] [Google Scholar] [Retracted]
  7. Gullis R. J., Rowe C. E. The stimulation by transmitter substances and putative transmitter substances of the net activity of phospholipase A2 of synaptic membranes of cortex of guinea-pig brain. Biochem J. 1975 May;148(2):197–208. doi: 10.1042/bj1480197. [DOI] [PMC free article] [PubMed] [Google Scholar] [Retracted]
  8. Gullis R. J., Rowe C. E. The stimulation of the phospholipase A2-acylation system of synaptic membranes of brain by cyclic nucleotides. Biochem J. 1975 Jun;148(3):567–581. doi: 10.1042/bj1480567. [DOI] [PMC free article] [PubMed] [Google Scholar] [Retracted]
  9. Hamprecht B., Gullis R. J. Statement. Nature. 1977 Feb 24;265(5596):764–764. doi: 10.1038/265764b0. [DOI] [PubMed] [Google Scholar]
  10. ROBERTSON A. F., LANDS W. E. Positional specificites in phospholipid hydrolyses. Biochemistry. 1962 Sep;1:804–810. doi: 10.1021/bi00911a012. [DOI] [PubMed] [Google Scholar]
  11. Rowe C. E., Gullis R. J. The effects of neurotransmitters and cyclic nucleotides on the metabolism of phospholipids in synaptic membranes of brain. Adv Exp Med Biol. 1976;72:211–225. doi: 10.1007/978-1-4684-0955-0_18. [DOI] [PubMed] [Google Scholar]

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