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. 1977 Jul 15;166(1):137–139. doi: 10.1042/bj1660137

Permeability of the mitochondrial membrane to bicarbonate ions.

M J Selwyn, H A Walker
PMCID: PMC1164966  PMID: 901413

Abstract

Osmotic-swelling techniques show that HCO3- enters mitochondria by an electrogenic process, effectively HCO3- uniport, under non-energized conditions. This mode of translocation accounts for previous reports of non-entry of HCO3- in experiments with energy-linked Ca2+ uptake. The effects of HCO3- on mitochondrial respiration are reported and discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ebel R. E., Lardy H. A. Stimulation of rat liver mitochondrial adenosine triphosphatase by anions. J Biol Chem. 1975 Jan 10;250(1):191–196. [PubMed] [Google Scholar]
  2. Elder J. A., Lehninger A. L. Respiration-dependent transport of carbon dioxide into rat liver mitochondria. Biochemistry. 1973 Feb 27;12(5):976–982. doi: 10.1021/bi00729a029. [DOI] [PubMed] [Google Scholar]
  3. Lehninger A. L. Role of phosphate and other proton-donating anions in respiration-coupled transport of Ca2+ by mitochondria. Proc Natl Acad Sci U S A. 1974 Apr;71(4):1520–1524. doi: 10.1073/pnas.71.4.1520. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Moyle J., Mitchell P. Electric charge stoicheiometry of calcium translocation in rat liver mitochondria. FEBS Lett. 1977 Feb 1;73(2):131–136. doi: 10.1016/0014-5793(77)80964-2. [DOI] [PubMed] [Google Scholar]
  5. Pedersen P. L. ATP-dependent reactions catalyzed by inner membrane vesicles of rat liver mitochondria. Kinetics, substrate specificity, and bicarbonate sensitivity. J Biol Chem. 1976 Feb 25;251(4):934–940. [PubMed] [Google Scholar]
  6. Selwyn M. J., Dawson A. P., Dunnett S. J. Calcium transport in mitochondria. FEBS Lett. 1970 Sep 18;10(1):1–5. doi: 10.1016/0014-5793(70)80402-1. [DOI] [PubMed] [Google Scholar]
  7. Selwyn M. J., Dawson A. P., Stockdale M., Gains N. Chloride-hydroxide exchange across mitochondrial, erythrocyte and artificial lipid membranes mediated by trialkyl- and triphenyltin compounds. Eur J Biochem. 1970 May 1;14(1):120–126. doi: 10.1111/j.1432-1033.1970.tb00268.x. [DOI] [PubMed] [Google Scholar]
  8. Stockdale M., Dawson A. P., Selwyn M. J. Effects of trialkyltin and triphenyltin compounds on mitochondrial respiration. Eur J Biochem. 1970 Aug;15(2):342–351. doi: 10.1111/j.1432-1033.1970.tb01013.x. [DOI] [PubMed] [Google Scholar]

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