Skip to main content
Biochemical Journal logoLink to Biochemical Journal
. 1973 Nov;135(3):573–576. doi: 10.1042/bj1350573

Ribonucleic acid–deoxyribonucleic acid hybridization as a second-order reaction (Short Communication)

Bryan D Young 1, John Paul 1
PMCID: PMC1165866  PMID: 4772283

Abstract

Certain features of RNA–DNA hybridization can be accounted for in terms of second-order-reaction theory. These include the use of annealing kinetics to estimate RNA complexity and the occurrence of approximately linear double-reciprocal plots.

Full text

PDF
575

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Birnstiel M. L., Sells B. H., Purdom I. F. Kinetic complexity of RNA molecules. J Mol Biol. 1972 Jan 14;63(1):21–39. doi: 10.1016/0022-2836(72)90519-0. [DOI] [PubMed] [Google Scholar]
  2. Bishop J. O. Examination of an equilibrium interpretation of deoxyribonucleic acid-ribonucleic acid hybridization data. Biochem J. 1970 Jan;116(2):223–228. doi: 10.1042/bj1160223. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Bishop J. O. The effect of genetic complexity on the time-course of ribonucleic acid-deoxyribonucleic acid hybridization. Biochem J. 1969 Aug;113(5):805–811. doi: 10.1042/bj1130805. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Britten R. J., Kohne D. E. Repeated sequences in DNA. Hundreds of thousands of copies of DNA sequences have been incorporated into the genomes of higher organisms. Science. 1968 Aug 9;161(3841):529–540. doi: 10.1126/science.161.3841.529. [DOI] [PubMed] [Google Scholar]
  5. Doty P., Marmur J., Eigner J., Schildkraut C. STRAND SEPARATION AND SPECIFIC RECOMBINATION IN DEOXYRIBONUCLEIC ACIDS: PHYSICAL CHEMICAL STUDIES. Proc Natl Acad Sci U S A. 1960 Apr;46(4):461–476. doi: 10.1073/pnas.46.4.461. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Laird C. D., McCarthy B. J. Magnitude of interspecific nucleotide sequence variability in Drosophila. Genetics. 1968 Oct;60(2):303–322. doi: 10.1093/genetics/60.2.303. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Lavallé R., De Hauwer G. Messenger RNA synthesis during amino acid starvation in Escherichia coli. J Mol Biol. 1968 Oct 28;37(2):269–288. doi: 10.1016/0022-2836(68)90267-2. [DOI] [PubMed] [Google Scholar]
  8. MARMUR J., DOTY P. Thermal renaturation of deoxyribonucleic acids. J Mol Biol. 1961 Oct;3:585–594. doi: 10.1016/s0022-2836(61)80023-5. [DOI] [PubMed] [Google Scholar]
  9. NYGAARD A. P., HALL B. D. FORMATION AND PROPERTIES OF RNA-DNA COMPLEXES. J Mol Biol. 1964 Jul;9:125–142. doi: 10.1016/s0022-2836(64)80095-4. [DOI] [PubMed] [Google Scholar]
  10. Paul J., Gilmour R. S. Organ-specific restriction of transcription in mammalian chromatin. J Mol Biol. 1968 Jul 14;34(2):305–316. doi: 10.1016/0022-2836(68)90255-6. [DOI] [PubMed] [Google Scholar]
  11. Paul J., Gilmour R. S. Template activity of DNA is restricted in chromatin. J Mol Biol. 1966 Mar;16(1):242–244. doi: 10.1016/s0022-2836(66)80276-0. [DOI] [PubMed] [Google Scholar]
  12. Wetmur J. G., Davidson N. Kinetics of renaturation of DNA. J Mol Biol. 1968 Feb 14;31(3):349–370. doi: 10.1016/0022-2836(68)90414-2. [DOI] [PubMed] [Google Scholar]

Articles from Biochemical Journal are provided here courtesy of The Biochemical Society

RESOURCES