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. 1986 Dec 1;5(12):3373–3379. doi: 10.1002/j.1460-2075.1986.tb04653.x

suc1 is an essential gene involved in both the cell cycle and growth in fission yeast

Jacqueline Hayles 1, Stephen Aves 1, Paul Nurse 1
PMCID: PMC1167336  PMID: 16453733

Abstract

The gene suc1 encodes a product which suppresses certain temperature sensitive mutants of the cell cycle control gene cdc2 of Schizosaccharomyces pombe. Mutants in the suc1 gene or over-expression of its product leads to delays in mitotic and meiotic nuclear division. Deletion of the suc1 gene is lethal and generates some cells blocked in the cell cycle and others impaired in cellular growth. It is likely that the suc1 gene product binds and forms unstable complexes with the cdc2 protein kinase and with other proteins necessary for the cell cycle and cellular growth. suc1 may have a regulatory role in these processes.

Keywords: cell cycle, extragenic suppressors, Schizosaccharomyces pombe, nuclear division

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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