Abstract
(±)-[14C]Amphetamine sulphate (20mg) was administered orally to each of two human male subjects, and 80–85% of the 14C was excreted in the urine in 2 days. The metabolites in the first day's urine were examined quantitatively. Apart from the metabolites previously described (Dring et al., 1970), norephedrine (2.2 and 2.6% of dose in the two subjects respectively) and 4-hydroxynorephedrine (0.3 and 0.4% of dose in the two subjects respectively) were also found.
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