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. 1971 Feb;121(3):447–452. doi: 10.1042/bj1210447

Formation of malate from glyoxylate in animal tissues

Chi-Chin Liang 1, Lo-Chang Ou 1,*
PMCID: PMC1176592  PMID: 5119782

Abstract

1. Incubation of rat liver homogenate with [1-14C]glyoxylate, ATP and acetate shows a rapid sequential incorporation of radioactivity into malate, oxaloacetate and citrate. 2. In liver from normal rats the rate of the formation of each substance in question is higher than that in liver from thiamin-deficient rats. 3. The net accumulation of malate is greater with liver from thiamin-deficient rats. Its further metabolism is retarded, it is suggested, by inhibitors formed by a condensation of glyoxylate and oxaloacetate.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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