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. 1971 Oct;124(5):915–919. doi: 10.1042/bj1240915

The preparation of an alkali-soluble collagen from demineralized bone

G D Kemp 1,*, G R Tristram 1
PMCID: PMC1177279  PMID: 4943353

Abstract

Ossein was solubilized by the action of alkali and a resulting high-molecular-weight fraction isolated. The chemical and physical properties of this fraction were studied and compared with those of an acid-soluble collagen prepared from calf skin by conventional techniques. From the results it is concluded that the alkali-soluble protein exhibits only minor differences from acid-soluble collagen, and that these differences can be ascribed for the most part to a decrease in the inter- and intramolecular cross-linking.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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