Skip to main content
PMC home page
Biochemical Journal logoLink to Biochemical Journal
. 1970 Nov;120(2):393–397. doi: 10.1042/bj1200393

Identification of the acrylate porphyrin S-411 from meconium

J French 1,2,3, D C Nicholson 1,2,3, C Rimington 1,2,3
PMCID: PMC1179610  PMID: 5493861

Abstract

A new porphyrin isolated from calf and foal meconium has been characterized as a tris-(2-carboxyethyl)-mono-(2-carboxyvinyl)-tetramethyl porphin, that is as an analogue of coproporphyrin in which one propionate group has been replaced by an acrylate group. The porphyrin is mainly a type III isomer and its possible significance in haem biosynthesis is discussed.

Full text

PDF
396-1

Images in this article

396-1PLATE 1
on p.396-1

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ERIKSEN L. Paper chromatographic separation of the coproporphyrin isomers I and III. Scand J Clin Lab Invest. 1958;10(3):319–322. [PubMed] [Google Scholar]
  2. French J. M., Thonger E. Ether-soluble porphyrins in bile, meconium and urine: a new appraisal by microscale counter-current analysis. Clin Sci. 1966 Dec;31(3):337–351. [PubMed] [Google Scholar]
  3. GRANICK S., LEVERE R. D. HEME SYNTHESIS IN ERYTHROID CELLS. Prog Hematol. 1964;4:1–47. [PubMed] [Google Scholar]
  4. Kennedy G. Y., Jackson A. H., Kenner G. W., Suckling C. J. Isolation, structure and synthesis of a tricarboxylic porphyrin from the harderian glands of the rat. FEBS Lett. 1970 Jan 15;6(1):9–12. doi: 10.1016/0014-5793(70)80027-8. [DOI] [PubMed] [Google Scholar]
  5. NICHOLAS R. E. H., RIMINGTON C. Paper chromatography of porphyrins; some hitherto unrecognized porphyrins and further notes on the method. Biochem J. 1951 Mar;48(3):306–309. doi: 10.1042/bj0480306. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. PORRA R. J., FALK J. E. Protein-bound porphyrins associated with protoporphyrin biosynthesis. Biochem Biophys Res Commun. 1961 Jun 28;5:179–184. doi: 10.1016/0006-291x(61)90106-1. [DOI] [PubMed] [Google Scholar]
  7. Rimington C. Porphyrins and Their Relation to the Metabolism of Blood Pigments: (Section of Therapeutics and Pharmacology). Proc R Soc Med. 1939 Aug;32(10):1268–1275. [PMC free article] [PubMed] [Google Scholar]
  8. SANO S., GRANICK S. Mitochondrial coproporphyrinogen oxidase and protoporphyrin formation. J Biol Chem. 1961 Apr;236:1173–1180. [PubMed] [Google Scholar]
  9. Sano S., Nanzyo N., Rimington C. Synthesis of porphyrin c-type compounds from protoporphyrinogen. Biochem J. 1964 Nov;93(2):270–280. doi: 10.1042/bj0930270. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. del Batlle A. M., Benson A., Rimington C. Purification and properties of coproporphyrinogenase. Biochem J. 1965 Dec;97(3):731–740. doi: 10.1042/bj0970731. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Biochemical Journal are provided here courtesy of The Biochemical Society

RESOURCES