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. 1970 Feb;116(4):563–567. doi: 10.1042/bj1160563

Characterization of rapidly labelled rat liver ribonucleic acid showing high affinity for columns of methylated albumin on kieselguhr

W Kunz 1, J Niessing 1, B Schnieders 1, C E Sekeris 1
PMCID: PMC1185400  PMID: 4314130

Abstract

Most of the rapidly labelled RNA from rat liver submitted to column chromatography on methylated albumin on kieselguhr remains tightly bound to the column and can only be recovered by elution with m-ammonia. The tightly bound RNA is composed mainly of DNA-like RNA. The binding capacity is dependent not only on base composition but also on molecular size: the heavier RNA molecules show a greater affinity to the column than do the lower-molecular-weight components. Rapidly labelled mouse liver and Saccharomyces cerevisiae RNA show similar behaviour to rat liver RNA on columns of methylated albumin on kieselguhr.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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