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. 1969 Feb;111(3):273–278. doi: 10.1042/bj1110273

Repression by glucose of acetohydroxy acid synthetase in Escherichia coli B

M B Coukell 1, W J Polglase 1
PMCID: PMC1187508  PMID: 4886117

Abstract

Acetolactate formation in Escherichia coli B results from the activity of a single system, acetohydroxy acid synthetase, which has a pH optimum of 8·0 and is sensitive to end-product inhibition by l-valine. Acetohydroxy acid synthetase was found to be subject to catabolite repression, and the nature and concentration of the carbon source had a greater effect on the formation of the enzyme than had the known end products (valine, isoleucine, leucine and pantothenate) of the biosynthetic pathways of which this enzyme is a member. The results suggest that acetohydroxy acid synthetase may play an amphibolic role in E. coli B.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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