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. 1997 Nov;226(5):582–586. doi: 10.1097/00000658-199711000-00002

A new macroscopic classification predicts prognosis for patient with liver metastases from colorectal cancer.

K Yasui 1, T Hirai 1, T Kato 1, A Torii 1, K Uesaka 1, T Morimoto 1, Y Kodera 1, Y Yamamura 1, T Kito 1, N Hamajima 1
PMCID: PMC1191119  PMID: 9389391

Abstract

OBJECTIVE: The authors defined a new macroscopic classification of liver metastases from colorectal cancer. SUMMARY BACKGROUND DATA: There were different prognostic results after the same operative procedure for liver metastases with similar background factors. METHODS: Eighty-one resected liver metastases were classified into simple nodular (SN) or confluent nodular (CN) types according to the characteristics of the cut surface of the tumor. RESULTS: The 5-year survival rates after hepatectomy were 41.7% for the SN lesions (n = 39) and 23.1% for the CN lesions (n = 42). The difference between the survival curves was statistically significant (p = 0.0307). Multivariate analysis using Cox's proportional hazards model revealed that the macroscopic type (p = 0.023), the tumor diameter (p = 0.0001), and the presence of lymph node metastases (p = 0.0016) were statistically significant independent prognostic factors. CONCLUSION: The new macroscopic classification may be valuable as a prognostic factor reflecting the biologic behavior of liver metastases.

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Selected References

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