Abstract
A total of 19,067 sera were screened for biological false positive (BFP) reactivity by the Venereal Disease Research Laboratory (VDRL) test. Sera which were reactive in the VDRL test were confirmed by the fluorescent treponemal antibody absorption (FTA-ABS) test. BFP reactions were detected in 0.59% of the general population, 0.72% of pregnant women and 11.8% of patients with systemic lupus erythematosus (SLE). The rate of BFP reactors among pregnant women did not differ significantly from the general population. The female to male ratio of BFP in the general population was 2:1 whilst that in the group of patients with SLE was 8:1. The overall seroprevalence of syphilis was 2.2%.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- Ashcroft M. T., Urquhart A. E. Treponemal serological tests in Jamaican school children, 1976. West Indian Med J. 1978 Mar;27(1):26–30. [PubMed] [Google Scholar]
- Catterall R. D. Presidential Address to the M.S.S.V.D. Systemic disease and the biological false positive reaction. Br J Vener Dis. 1972 Feb;48(1):1–12. doi: 10.1136/sti.48.1.1. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Diggory P. Role of the Venereal Disease Research Laboratory test in the detection of syphilis. Br J Vener Dis. 1983 Feb;59(1):8–10. doi: 10.1136/sti.59.1.8. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Felman Y. M., Nikitas J. A. Syphilis serology today. Arch Dermatol. 1980 Jan;116(1):84–89. [PubMed] [Google Scholar]
- Fiumara N. J. Treatment of secondary syphilis: an evaluation of 204 patients. Sex Transm Dis. 1977 Jul-Sep;4(3):96–99. doi: 10.1097/00007435-197707000-00005. [DOI] [PubMed] [Google Scholar]
- Gibowski M., Neumann E. Non-specific positive test results to syphilis in dermatological diseases. Br J Vener Dis. 1980 Feb;56(1):17–19. doi: 10.1136/sti.56.1.17. [DOI] [PMC free article] [PubMed] [Google Scholar]
- HUNTER E. F., DEACON W. E., MEYER P. E. AN IMPROVED FTA TEST FOR SYPHILIS, THE ABSORPTION PROCEDURE (FTA-ABS). Public Health Rep. 1964 May;79:410–412. [PMC free article] [PubMed] [Google Scholar]
- Hossain A. Serological tests for syphilis in Saudi Arabia. Genitourin Med. 1986 Oct;62(5):293–297. doi: 10.1136/sti.62.5.293. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hughes G. R. The anticardiolipin syndrome. Clin Exp Rheumatol. 1985 Oct-Dec;3(4):285–286. [PubMed] [Google Scholar]
- Kaufman R. E., Weiss S., Moore J. D., Falcone V., Wiesner P. J. Biological false positive serological tests for syphilis among drug addicts. Br J Vener Dis. 1974 Oct;50(5):350–353. doi: 10.1136/sti.50.5.350. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Luger A., Schmidt B., Spendlingwimmer I., Horn F. Recent observations on the serology of syphilis. Br J Vener Dis. 1980 Feb;56(1):12–16. doi: 10.1136/sti.56.1.12. [DOI] [PMC free article] [PubMed] [Google Scholar]
- MOORE J. E., MOHR C. F. Biologically false positive serologic tests for syphilis; type, incidence, and cause. J Am Med Assoc. 1952 Oct 4;150(5):467–473. doi: 10.1001/jama.1952.03680050033010. [DOI] [PubMed] [Google Scholar]
- Salo O. P., Aho K., Nieminen E., Hormila P. False-positive serological test for syphilis in pregnancy. Acta Derm Venereol. 1969;49(3):332–335. [PubMed] [Google Scholar]
- Tomizawa T., Kasamatsu S., Yamaya S. I. Usefulness of the hemagglutination test using Treponema pallidum antigen (TPHA) for the serodiagnosis of syphilis. Jpn J Med Sci Biol. 1969 Dec;22(6):341–350. doi: 10.7883/yoken1952.22.341. [DOI] [PubMed] [Google Scholar]
- Wilson W. A., Hughes G. R. Rheumatic disease in Jamaica. Ann Rheum Dis. 1979 Aug;38(4):320–325. doi: 10.1136/ard.38.4.320. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Yokohari R., Tsunematsu T. Application, to Japanese patients, of the 1982 American Rheumatism Association revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum. 1985 Jun;28(6):693–698. doi: 10.1002/art.1780280614. [DOI] [PubMed] [Google Scholar]
- Young H., Henrichsen C., Robertson D. H. Treponema pallidum haemagglutination test as a screening procedure for the diagnosis of syphilis. Br J Vener Dis. 1974 Oct;50(5):341–346. doi: 10.1136/sti.50.5.341. [DOI] [PMC free article] [PubMed] [Google Scholar]