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. 1995 Aug;71(4):244–246. doi: 10.1136/sti.71.4.244

Azithromycin levels in cervical mucus and plasma after a single 1.0g oral dose for chlamydial cervicitis.

A M Worm 1, A Osterlind 1
PMCID: PMC1195522  PMID: 7590717

Abstract

OBJECTIVE--To determine the kinetics of azithromycin in cervical mucus and plasma. SUBJECTS AND METHODS--Azithromycin concentrations were determined in plasma and mucus samples from 20 women with cervical chlamydial infection one, seven and fourteen days after a single oral 1.0 g dose. RESULTS--In mucus, all measurable azithromycin concentrations were above the minimal inhibitory concentration against Chlamydia trachomatis on day 7 as well as on day 14. CONCLUSION--The high cervical mucus concentrations of azithromycin can explain the high clinical and microbiological efficacy.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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