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. 1967 Nov;105(2):709–716. doi: 10.1042/bj1050709

Fatty acid synthesis in intestinal mucosa of guinea pig

M J Tame 1, R Dils 1
PMCID: PMC1198368  PMID: 4384598

Abstract

1. Acetate–CoA ligase, acetyl-CoA–carbon dioxide ligase and fatty acid synthetase were shown to be present in particle-free fractions of guinea-pig intestinal mucosa. 2. Each of these enzymes was partially purified by ammonium sulphate precipitation from the particle-free supernatant. 3. The incorporation of acetate and citrate into fatty acid was measured. 4. Gas–liquid radiochromatography was used to investigate the pattern of fatty acids synthesized. 5. The rate-limiting step in fatty acid synthesis was shown to be acetyl-CoA–carbon dioxide ligase.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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