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. 1968 Jan;106(2):497–501. doi: 10.1042/bj1060497

Androgen sulphate formation in male and female rats

D A Lewis 1,*
PMCID: PMC1198529  PMID: 5637356

Abstract

1. After large doses of androsterone, epiandrosterone, dehydroepiandrosterone and testosterone, female rats excreted more of the dose conjugated with sulphuric acid than did the males. 2. Androgens were also incubated with liver slices from male and female rats. Slices from females conjugated androgens with sulphuric acid to a greater extent than did slices from males. 3. The amount of unchanged androgen present in the faeces of orally dosed animals was 4–35% of the dose.

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Selected References

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