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. 1963 Dec;89(3):438–447. doi: 10.1042/bj0890438

Protein breakdown in the brain. Subcellular distribution and properties of neutral and acid proteinases

N Marks 1, A Lajtha 1
PMCID: PMC1202448  PMID: 14101962

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ACS G., NEIDLE A., WAELSCH H. Brain ribosomes and amino acid incorporation. Biochim Biophys Acta. 1961 Jun 24;50:403–404. doi: 10.1016/0006-3002(61)90356-0. [DOI] [PubMed] [Google Scholar]
  2. ADAMS C. W., BAYLISS O. B. Histochemistry of myelin. III. Peripheral nerve cathepsin. J Histochem Cytochem. 1961 Sep;9:473–476. doi: 10.1177/9.5.473. [DOI] [PubMed] [Google Scholar]
  3. ADAMS E., SMITH E. L. Proteolytic activity of pituitary extracts. J Biol Chem. 1951 Aug;191(2):651–664. [PubMed] [Google Scholar]
  4. ALDRIDGE W. N., EMERY R. C., STREET B. W. A tissue homogenizer. Biochem J. 1960 Nov;77:326–327. doi: 10.1042/bj0770326. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. ANFINSEN C. B., STEINBERG D., VAUGHAN M. Kinetic aspects of assembly and degradation of proteins. Science. 1956 Aug 31;124(3218):389–395. doi: 10.1126/science.124.3218.389. [DOI] [PubMed] [Google Scholar]
  6. ANSELL G. B., RICHTER D. Evidence for a neutral proteinase in brain tissue. Biochim Biophys Acta. 1954 Jan;13(1):92–97. doi: 10.1016/0006-3002(54)90276-0. [DOI] [PubMed] [Google Scholar]
  7. BOUGHTON B., MACKENNA R. M., WHEATLEY V. R., WORMALL A. Studies of sebum. VIII. Observations on the squalene and cholesterol content and the possible functions of squalene in human sebum. Biochem J. 1957 May;66(1):32–38. doi: 10.1042/bj0660032. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. DOUNCE A. L., WITTER R. F., MONTY K. J., PATE S., COTTONE M. A. A method for isolating intact mitochondria and nuclei from the same homogenate, and the influence of mitochondrial destruction on the properties of cell nuclei. J Biophys Biochem Cytol. 1955 Mar;1(2):139–153. doi: 10.1083/jcb.1.2.139. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. FRUTON J. S. Enzymic hydrolysis and synthesis of peptide bonds. Harvey Lect. 1955;51:64–87. [PubMed] [Google Scholar]
  10. HANSON H., HERMANN P., BLECH W. [Acylase- and catheptic carboxypeptidase activity in the liver and kidney of rats and in the cellular components of these organs]. Hoppe Seylers Z Physiol Chem. 1959 Aug 6;315:201–207. doi: 10.1515/bchm2.1959.315.1.201. [DOI] [PubMed] [Google Scholar]
  11. HANZON V., TOSCHI G. Centrifugation of brain microsomes in a density gradient. Exp Cell Res. 1960 Nov;21:332–346. doi: 10.1016/0014-4827(60)90265-2. [DOI] [PubMed] [Google Scholar]
  12. HEALD P. J. Studies on the phosphoproteins of brain: the intracellular localization in brain of a phosphoprotein involved in the metabolic response of cortical slices to electrical stimulation. Biochem J. 1959 Sep;73:132–141. doi: 10.1042/bj0730132. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. HEBB C. O., WHITTAKER V. P. Intracellular distributions of acetylcholine and choline acetylase. J Physiol. 1958 Jun 18;142(1):187–196. doi: 10.1113/jphysiol.1958.sp006008. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. KOENIG H. Histological distribution of brain gangliosides: lysosomes as glycolipoprotein granules. Nature. 1962 Aug 25;195:782–784. doi: 10.1038/195782a0. [DOI] [PubMed] [Google Scholar]
  15. KORNER A., TARVER H. Studies on protein synthesis in vitro. VI. Incorporation and release of amino acids in particulate preparations from livers of rats. J Gen Physiol. 1957 Sep 20;41(1):219–231. doi: 10.1085/jgp.41.1.219. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. KUFF E. L., SCHNEIDER W. C. Intracellular distribution of enzymes. XII. Biochemical heterogeneity of mitochondria. J Biol Chem. 1954 Feb;206(2):677–685. [PubMed] [Google Scholar]
  17. LOWRY O. H., ROSEBROUGH N. J., FARR A. L., RANDALL R. J. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951 Nov;193(1):265–275. [PubMed] [Google Scholar]
  18. MARTIN C. J. Purification of a proteinase A inhibitor from sheep serum. J Biol Chem. 1961 Oct;236:2672–2676. [PubMed] [Google Scholar]
  19. MOORE S., STEIN W. H. Chromatography of amino acids on sulfonated polystyrene resins. J Biol Chem. 1951 Oct;192(2):663–681. [PubMed] [Google Scholar]
  20. NOVIKOFF A. B., ESSNER E. Pathological changes in cytoplasmic organelles. Fed Proc. 1962 Nov-Dec;21:1130–1142. [PubMed] [Google Scholar]
  21. OGAWA K., MIZUNO N., OKAMOTO M. Lysosomes in cultured cells. J Histochem Cytochem. 1961 Mar;9:202–202. doi: 10.1177/9.2.202. [DOI] [PubMed] [Google Scholar]
  22. OKUNUKI K. Denaturation and inactivation of enzyme proteins. Adv Enzymol Relat Subj Biochem. 1961;23:29–82. doi: 10.1002/9780470122686.ch2. [DOI] [PubMed] [Google Scholar]
  23. PETRUSHKA E., GIUDITTA A. Electron microscopy of two subcellular fractions isolated from cerebral cortex homogenate. J Biophys Biochem Cytol. 1959 Aug;6(1):129–132. doi: 10.1083/jcb.6.1.129. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. PRESS E. M., PORTER R. R., CEBRA J. The isolation and properties of a proteolytic enzyme, cathepsin D, from bovine spleen. Biochem J. 1960 Mar;74:501–514. doi: 10.1042/bj0740501. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. RADEMAKER W., SOONS J. B. The distribution of protease activities on liver cell fractions. Biochim Biophys Acta. 1957 May;24(2):451–452. doi: 10.1016/0006-3002(57)90232-9. [DOI] [PubMed] [Google Scholar]
  26. SIMPSON M. V. The release of labeled amino acids from the proteins of rat liver slices. J Biol Chem. 1953 Mar;201(1):143–154. [PubMed] [Google Scholar]
  27. VAN HEYNINGEN R., WALEY S. G. Neutral proteinases in the lens. 2. Partial purification and properties. Biochem J. 1963 Jan;86:92–101. doi: 10.1042/bj0860092. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. WAELSCH H., LAJTHA A. Protein metabolism in the nervous system. Physiol Rev. 1961 Oct;41:709–736. doi: 10.1152/physrev.1961.41.4.709. [DOI] [PubMed] [Google Scholar]
  29. WALEY S. G., VAN HEYNINGEN R. Neutral proteinases in the lens. Biochem J. 1962 May;83:274–283. doi: 10.1042/bj0830274. [DOI] [PMC free article] [PubMed] [Google Scholar]
  30. WHITTAKER V. P. The isolation and characterization of acetylcholine-containing particles from brain. Biochem J. 1959 Aug;72:694–706. doi: 10.1042/bj0720694. [DOI] [PMC free article] [PubMed] [Google Scholar]

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