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. 1973 Jan;73(1):1–11. doi: 10.1093/genetics/73.1.1

Selective Allele Loss in Mixed Infections with T4 Bacteriophage

Wendy C Benz 1, Hillard Berger 1
PMCID: PMC1212872  PMID: 4265784

Abstract

Evidence is presented that when E. coli B is mixedly infected with T4D wild type and rII deletion mutants, the excess DNA of the wild type allele is lost. No loss is seen in mixed infections with rII point mutants and wild type. In similar experiments with lysozyme addition mutants, the mutant allele is lost. We believe these results demonstrate a repair system which removes "loops" in heteroduplex DNA molecules. A number of phage and host functions have been tested for involvement in the repair of the excess DNA, and T4 genes x and v have been implicated in this process.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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