Skip to main content
PMC home page
The Journal of Physiology logoLink to The Journal of Physiology
. 1982;328:449–459. doi: 10.1113/jphysiol.1982.sp014276

Spontaneous and evoked excitatory junction potentials in rat tail arteries.

D W Cheung
PMCID: PMC1225670  PMID: 7131321

Abstract

1. The frequency, amplitude and time course of spontaneous excitatory junction potentials (s.e.j.p.s) and their relationship to the time course and amplitude of evoked excitatory junction potentials (e.j.p.s) were examined. 2. The frequency and amplitude of s.e.j.p.s varied dramatically between cells. There was good correlation between their rise and decay times. 3. The amplitude and time course of e.j.p.s also varied between cells. E.j.p.s with large amplitudes and fast time courses were recorded in cells with high s.e.j.p. frequencies. 4. Active responses propagated only for very limited distances. 5. The frequency of s.e.j.p.s decreased after reserpine and 6-hydroxydopamine (6-OHDA) treatments, suggesting that s.e.j.p.s were related to spontaneous release of noradrenaline from nerve terminals.

Full text

PDF
451

Images in this article

458-2Plate 1
on p.458-2

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BURKE W., GINSBORG B. L. The electrical properties of the slow muscle fibre membrane. J Physiol. 1956 Jun 28;132(3):586–598. doi: 10.1113/jphysiol.1956.sp005551. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. BURKE W. Spontaneous potentials in slow muscle fibres of the frog. J Physiol. 1957 Mar 11;135(3):511–521. doi: 10.1113/jphysiol.1957.sp005726. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. BURNSTOCK G., HOLMAN M. E. Spontaneous potential at sympathetic nerve endings in smooth muscle. J Physiol. 1962 Mar;160:446–460. doi: 10.1113/jphysiol.1962.sp006858. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Bell C. Transmission from vasoconstrictor and vasodilator nerves to single smooth muscle cells of the guinea-pig uterine artery. J Physiol. 1969 Dec;205(3):695–708. doi: 10.1113/jphysiol.1969.sp008991. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Bonaccorsi A., Hermsmeyer K., Smith C. B., Bohr D. F. Norepinephrine release in isolated arteries induced by K-free solution. Am J Physiol. 1977 Feb;232(2):H140–H145. doi: 10.1152/ajpheart.1977.232.2.H140. [DOI] [PubMed] [Google Scholar]
  6. Cheung D. W. Two components in the cellular response of rat tail arteries to nerve stimulation. J Physiol. 1982 Jul;328:461–468. doi: 10.1113/jphysiol.1982.sp014277. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Dennis M. J., Harris A. J., Kuffler S. W. Synaptic transmission and its duplication by focally applied acetylcholine in parasympathetic neurons in the heart of the frog. Proc R Soc Lond B Biol Sci. 1971 Apr 27;177(1049):509–539. doi: 10.1098/rspb.1971.0045. [DOI] [PubMed] [Google Scholar]
  8. GINSBORG B. L. Spontaneous activity in muscle fibres of the chick. J Physiol. 1960 Mar;150:707–717. doi: 10.1113/jphysiol.1960.sp006413. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Hirst G. D., Neild T. O. An analysis of excitatory junctional potentials recorded from arterioles. J Physiol. 1978 Jul;280:87–104. doi: 10.1113/jphysiol.1978.sp012374. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Hirst G. D., Neild T. O. Some properties of spontaneous excitatory junction potentials recorded from arterioles of guinea-pigs. J Physiol. 1980 Jun;303:43–60. doi: 10.1113/jphysiol.1980.sp013269. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Holman M. E., Surprenant A. M. Some properties of the excitatory junction potentials recorded from saphenous arteries of rabbits. J Physiol. 1979 Feb;287:337–351. doi: 10.1113/jphysiol.1979.sp012663. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. KUFFLER S. W., VAUGHAN WILLIAMS E. M. Small-nerve junctional potentials; the distribution of small motor nerves to frog skeletal muscle, and the membrane characteristics of the fibres they innervate. J Physiol. 1953 Aug;121(2):289–317. doi: 10.1113/jphysiol.1953.sp004948. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. KURIYAMA H., TOMITA T. THE RESPONSES OF SINGLE SMOOTH MUSCLE CELLS OF GUINEA-PIG TAENIA COLI TO INTRACELLULARLY APPLIED CURRENTS, AND THEIR EFFECT ON THE SPONTANEOUS ELECTRICAL ACTIVITY. J Physiol. 1965 May;178:270–289. doi: 10.1113/jphysiol.1965.sp007627. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Purves R. D. Current flow and potential in a three-dimensional syncytium. J Theor Biol. 1976 Jul 21;60(01):147–162. doi: 10.1016/0022-5193(76)90160-0. [DOI] [PubMed] [Google Scholar]
  15. Surprenant A. A comparative study of neuromuscular transmission in several mammalian muscular arteries. Pflugers Arch. 1980 Jul;386(1):85–91. doi: 10.1007/BF00584192. [DOI] [PubMed] [Google Scholar]
  16. Suzuki H., Kuriyama H. Observation of quantal release of noradrenaline from vascular smooth muscles in potassium-free solution. Jpn J Physiol. 1980;30(4):665–670. doi: 10.2170/jjphysiol.30.665. [DOI] [PubMed] [Google Scholar]
  17. Tomita T. Current spread in the smooth muscle of the guinea-pig vas deferens. J Physiol. 1967 Mar;189(1):163–176. doi: 10.1113/jphysiol.1967.sp008161. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Tomita T. Spike propagation in the smooth muscle of the guinea-pig taenia coli. J Physiol. 1967 Aug;191(3):517–527. doi: 10.1113/jphysiol.1967.sp008265. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Torre J. C., Surgeon J. W. A methodological approach to rapid and sensitive monoamine histofluorescence using a modified glyoxylic acid technique: the SPG method. Histochemistry. 1976 Oct 22;49(2):81–93. doi: 10.1007/BF00495672. [DOI] [PubMed] [Google Scholar]

Articles from The Journal of Physiology are provided here courtesy of The Physiological Society

RESOURCES