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. 1984 Oct;48(4):354–359.

Effects of gonadotrophin releasing hormone on reproductive performance of dairy cows with retained placenta.

K E Leslie, P A Doig, W T Bosu, R A Curtis, S W Martin
PMCID: PMC1236082  PMID: 6391640

Abstract

The effects of gonadotrophin releasing hormone (GnRH) on the reproductive performance of dairy cows with retained placenta were studied. Three hundred and seventy-eight cows diagnosed as having retained placenta received intramuscular injections of either 2 mL sterile water or 200 micrograms of GnRH in 2 mL sterile water between day 8 and day 14 postpartum. Rectal palpation was performed at the time of treatment and ten to 20 days after treatment in order to determine the rate of uterine involution. Thereafter, monthly rectal examinations were carried out until insemination. Pregnancy diagnosis was made by rectal palpation at 40 days or more after breeding. Using the entire experimental population, there were no significant differences between GnRH-treated and control cows for the rate of uterine involution, the occurrence of reproductive problems, the interval from parturition to first observed estrus, the interval from parturition to first insemination, the interval from parturition to conception, the number of services per conception, the total number of services per cow regardless of conception and the incidence of culling for infertility. When the data for herds in which breeding began earlier in the postpartum period (herds having a mean less than or equal to 80 days from parturition to first service for retained placenta cows) were considered, the GnRH treatment resulted in a significantly shorter (p less than or equal to 0.01) calving to conception interval as compared to control cows. Also, there was a significant reduction (p less than or equal to 0.05) in the total number of services per cow regardless of conception and a significant reduction in the interval from parturition to first service.(ABSTRACT TRUNCATED AT 250 WORDS)

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bostedt H., Peche E., Strobl K. Zur Auswirkung frühzeitig post partum verabreichter GnRH-Gaben auf Puerperalverlauf und Konzeptionsergebnis bei Kühen nach Retentio secundinarum. Berl Munch Tierarztl Wochenschr. 1980 May 15;93(10):184–188. [PubMed] [Google Scholar]
  2. Britt J. H. Early postpartum breeding in dairy cows. A review. J Dairy Sci. 1975 Feb;58(2):266–271. doi: 10.3168/jds.S0022-0302(75)84558-9. [DOI] [PubMed] [Google Scholar]
  3. Britt J. H., Harrison D. S., Morrow D. A. Frequency of ovarian follicular cysts, reasons for culling, and fertility in Holstein-Friesian cows given gonadotropin-releasing hormone at two weeks after parturition. Am J Vet Res. 1977 Jun;38(6):749–751. [PubMed] [Google Scholar]
  4. ERB R. E., HINZE P. M., GILDOW E. M., MORRISON R. A. Retained fetal membranes: the effect on prolificacy of dairy cattle. J Am Vet Med Assoc. 1958 Nov 15;133(10):489–496. [PubMed] [Google Scholar]
  5. Etherington W. G., Bosu W. T., Martin S. W., Cote J. F., Doig P. A., Leslie K. E. Reproductive performance in dairy cows following postpartum treatment with gonadotrophin releasing hormone and/or prostaglandin: a field trial. Can J Comp Med. 1984 Jul;48(3):245–250. [PMC free article] [PubMed] [Google Scholar]
  6. Foster J. P., Lamming G. E., Peters A. R. Short-term relationships between plasma LH, FSH and progesterone concentrations in post-partum dairy cows and the effect of Gn-RH injection. J Reprod Fertil. 1980 Jul;59(2):321–327. doi: 10.1530/jrf.0.0590321. [DOI] [PubMed] [Google Scholar]
  7. Garverick H. A., Elmore R. G., Vaillancourt D. H., Sharp A. J. Ovarian response to gonadotropin-releasing hormone in postpartum dairy cows. Am J Vet Res. 1980 Oct;41(10):1582–1585. [PubMed] [Google Scholar]
  8. Kesler D. J., Garverick H. A., Youngquist R. S., Elmore R. G., Bierschwal C. J. Effect of days postpartum and endogenous reproductive hormones on GNRH-induced LH release in dairy cows. J Anim Sci. 1977 Oct;45(4):797–803. doi: 10.2527/jas1977.454797x. [DOI] [PubMed] [Google Scholar]
  9. Leslie K. E. The effects of gonadotrophin releasing hormone administration in early postpartum dairy cows on hormone concentrations, ovarian activity and reproductive performance: a review. Can Vet J. 1983 Apr;24(4):116–122. [PMC free article] [PubMed] [Google Scholar]
  10. Marion G. B., Norwood J. S., Gier H. T. Uterus of the cow after parturition: factors affecting regression. Am J Vet Res. 1968 Jan;29(1):71–75. [PubMed] [Google Scholar]
  11. Nash J. G., Jr, Ball L., Olson J. D. Effects on reproductive performance of administration of GnRH to early postpartum dairy cows. J Anim Sci. 1980 Jun;50(6):1017–1021. doi: 10.2527/jas1980.5061017x. [DOI] [PubMed] [Google Scholar]
  12. Sandals W. C., Curtis R. A., Cote J. F., Martin S. W. The effect of retained placenta and metritis complex on reproductive performance in dairy cattle -- a case control study. Can Vet J. 1979 May;20(5):131–135. [PMC free article] [PubMed] [Google Scholar]
  13. Tennant B., Peddicord R. G. The influence of delayed uterine involution and endometritis on bovine fertility. Cornell Vet. 1968 Apr;58(2):185–192. [PubMed] [Google Scholar]
  14. Thatcher W. W., Wilcox C. J. Postpartum estrus as an indicator of reproductive status in the dairy cow. J Dairy Sci. 1973 May;56(5):608–610. doi: 10.3168/jds.S0022-0302(73)85227-0. [DOI] [PubMed] [Google Scholar]
  15. Whitmore H. L., Tyler W. J., Casida L. E. Effects of early postpartum breeding in dairy cattle. J Anim Sci. 1974 Feb;38(2):339–346. doi: 10.2527/jas1974.382339x. [DOI] [PubMed] [Google Scholar]
  16. Zaied A. A., Garverick H. A., Bierschwal C. J., Elmore R. G., Youngquist R. S., Sharp A. J. Effect of ovarian activity and endogenous reproductive hormones on GnRH-induced ovarian cycles in postpartum dairy cows. J Anim Sci. 1980 Mar;50(3):508–513. doi: 10.2527/jas1980.503508x. [DOI] [PubMed] [Google Scholar]
  17. Zolman J., Convey E. M., Britt J. H. Relationships between the luteinizing hormone response to gonadotropin releasing hormone and endogenous steroids. J Anim Sci. 1974 Aug;39(2):355–359. doi: 10.2527/jas1974.392355x. [DOI] [PubMed] [Google Scholar]

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