RETRACTED: Qureshi et al. Synthesis and Evaluation of Anti-HIV Activity of Mono- and Di-Substituted Phosphonamidate Conjugates of Tenofovir. Molecules 2022, 27, 4447

The journal retracts the article entitled “Synthesis and Evaluation of Anti-HIV Activity of Mono- and Di-Substituted Phosphonamidate Conjugates of Tenofovir” [1], cited above.

Following publication, the corresponding authors, on behalf of all the authors, brought concerns to the attention of the publisher regarding the validity of the NMR and mass spectra data presented in this article [1]. These concerns were brought to the Editorial Office voluntarily in the interest of upholding the integrity of the scientific record.

Adhering to our standard procedure, an investigation was conducted by the Editorial Office and Editorial Board, with input provided by an internal institutional investigation by H.E.J. Research Institute, conducted at the request of the corresponding author. During the follow-up process, the Editorial Board invited the authors to directly address the concerns and prepare a potential post-publication amendment to the article. Following a review of this proposal, the Editorial Boad determined that this proposal could not sufficiently address the concerns without a significant impact on the study’s central findings. As a result, the Editorial Board have decided to retract this article [1] as per MDPI’s retraction policy (https://www.mdpi.com/ethics#_bookmark30, accessed on 10 July 2025). The authors are invited to present revised findings in a new manuscript.

This retraction was approved by the authors and by the Editor-in-Chief of Molecules.

Louise A. Ouattara, Naglaa Salem El-Sayed, Amita Verma, Gustavo F. Doncel, Muhammad Iqbal Choudhary, Hina Siddiqui, and Keykavous Parang agreed to this retraction. The remaining author did not provide a comment on this decision.