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. 1981 Jun;315:231–242. doi: 10.1113/jphysiol.1981.sp013744

The effect of knee joint afferent discharge on transmission in flexion reflex pathways in decerebrate cats.

R H Baxendale, W R Ferrell
PMCID: PMC1249379  PMID: 7310709

Abstract

1. Changes in excitability of reflex arcs mediating flexion withdrawal ad crossed extensor reflexes have been examined in decerebrate cats. 2. The excitability of flexion withdrawal and crossed extensor reflexes was shown to be modulated by knee joint position. Flexion withdrawal reflexes were most easily elicited when the knee was extended and crossed extensor reflexes were most easily elicited when the knee was flexed. 3. The modulation of transmission was not confined to reflex pathways to muscles acting at the knee but also included pathways to muscles acting at the hip and ankle, as well as pathways to muscles in the contralateral limb. 4. The changing excitability of reflex pathways caused by movement of the knee joint was unrelated to the stretch applied to muscles acting at the knee and to cutaneous afferent discharge. Modulation of reflex excitability by joint movement was totally abolished by local anaesthesia of the knee joint in an otherwise intact limb. 5. The results of the present experiments indicate that transmission in flexion reflex pathways can be inhibited by knee joint afferent discharge.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BESWICK F. B., BLOCKEY N. J., EVANSON J. M. Some effects of the stimulation of articular nerves. J Physiol. 1955 Jun 28;128(3):83P–83P. [PubMed] [Google Scholar]
  2. Baxendale R. H., Ferrell W. R. Modulation of transmission in flexion reflex pathways by knee joint afferent discharge in the decerebrate cat. Brain Res. 1980 Dec 8;202(2):497–500. doi: 10.1016/0006-8993(80)90163-8. [DOI] [PubMed] [Google Scholar]
  3. COHEN L. A., COHEN M. L. Arthrokinetic reflex of the knee. Am J Physiol. 1956 Feb;184(2):433–437. doi: 10.1152/ajplegacy.1956.184.2.433. [DOI] [PubMed] [Google Scholar]
  4. Clark F. J., Burgess P. R. Slowly adapting receptors in cat knee joint: can they signal joint angle? J Neurophysiol. 1975 Nov;38(6):1448–1463. doi: 10.1152/jn.1975.38.6.1448. [DOI] [PubMed] [Google Scholar]
  5. ECCLES R. M., LUNDBERG A. Supraspinal control of interneurones mediating spinal reflexes. J Physiol. 1959 Oct;147:565–584. doi: 10.1113/jphysiol.1959.sp006262. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Ferrell W. R. The adequacy of stretch receptors in the cat knee joint for signalling joint angle throughout a full range of movement. J Physiol. 1980 Feb;299:85–99. doi: 10.1113/jphysiol.1980.sp013112. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Freeman M. A., Wyke B. Articular reflexes at the ankle joint: an electromyographic study of normal and abnormal influences of ankle-joint mechanoreceptors upon reflex activity in the leg muscles. Br J Surg. 1967 Dec;54(12):990–1001. doi: 10.1002/bjs.1800541204. [DOI] [PubMed] [Google Scholar]
  8. Freeman M. A., Wyke B. The innervation of the knee joint. An anatomical and histological study in the cat. J Anat. 1967 Jun;101(Pt 3):505–532. [PMC free article] [PubMed] [Google Scholar]
  9. GARDNER E. Reflex muscular response to stimulation of articular nerves in the cat. Am J Physiol. 1950 Apr 1;161(1):133–141. doi: 10.1152/ajplegacy.1950.161.1.133. [DOI] [PubMed] [Google Scholar]
  10. Grigg P., Harrigan E. P., Fogarty K. E. Segmental reflexes mediated by joint afferent neurons in cat knee. J Neurophysiol. 1978 Jan;41(1):9–14. doi: 10.1152/jn.1978.41.1.9. [DOI] [PubMed] [Google Scholar]
  11. Lundberg A., Malmgren K., Schomburg E. D. Role of joint afferents in motor control exemplified by effects on reflex pathways from Ib afferents. J Physiol. 1978 Nov;284:327–343. doi: 10.1113/jphysiol.1978.sp012543. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. McCall W. D., Jr, Farias M. C., Williams W. J., BeMent S. L. Static and dynamic responses of slowly adapting joint receptors. Brain Res. 1974 Apr 19;70(2):221–243. doi: 10.1016/0006-8993(74)90314-x. [DOI] [PubMed] [Google Scholar]
  13. Ramcharan J. E., Wyke B. Articular reflexes at the knee joint: an electromyographic study. Am J Physiol. 1972 Dec;223(6):1276–1280. doi: 10.1152/ajplegacy.1972.223.6.1276. [DOI] [PubMed] [Google Scholar]
  14. Rossignol S., Gauthier L. An analysis of mechanisms controlling the reversal of crossed spinal reflexes. Brain Res. 1980 Jan 20;182(1):31–45. doi: 10.1016/0006-8993(80)90828-8. [DOI] [PubMed] [Google Scholar]
  15. SKOGLUND S. Anatomical and physiological studies of knee joint innervation in the cat. Acta Physiol Scand Suppl. 1956;36(124):1–101. [PubMed] [Google Scholar]

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