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. 1991 Jul;60(1):81–88. doi: 10.1016/S0006-3495(91)82032-X

Electrostatic modeling of dipole-ion interactions in gramicidinlike channels

M Sancho 1, G Martínez 1
PMCID: PMC1260040  PMID: 19431797

Abstract

Using an electrostatic model for the pore and membrane region in a gramicidinlike channel, the effect of dipoles located inside the membrane on the ion transport are analyzed. Calculated energy profiles for different orientations of dipoles show a predominant influence of their radial components. The results qualitatively agree with experimental measurements of conductance on different modified gramicidins and allow to understand the important role of polar side chains on ion permeation.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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