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. 1967 Jan;102(1):110–119. doi: 10.1042/bj1020110

The composition and physicochemical properties of bovine nasal-septa protein–polysaccharide complex

Mollie Luscombe 1, C F Phelps 1
PMCID: PMC1270216  PMID: 4226525

Abstract

1. Protein–polysaccharide complexes were prepared in three different ways and the gross stoicheiometry of the complexes compared. 2. The neutral sugar content was ascertained and the possibility of a glycoprotein occurring with chondroitin sulphate and keratosulphate is discussed. 3. Physical data support a molecule of molecular weight 3·2×106–5·8×106 with a roughly spherical domain and an average radius of gyration of 1390Å. Such a particle is highly solvated. The complex is heavily charged with the sulphate groups on the outside. 4. These findings are discussed in the light of the physiological role of protein–polysaccharide light fraction (PPL) in cartilage.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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