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. 1979 Sep;131(3):196–200.

Candida Pneumonia

Experience With 20 Patients

Zab Mohsenifar 1, Sawtantra K Chopra 1, B Lamar Johnson Jr 1, Daniel H Simmons 1
PMCID: PMC1271768  PMID: 18748467

Abstract

Case reports of 20 patients with histologic evidence of Candida pneumonia at autopsy were studied retrospectively. Most of the patients had had malignant conditions or immunosuppressive disorders, or had been treated by immunosuppressive agents such as steroids. Clinical findings included cough, purulent sputum and invariable hypoxia. Of the 20 patients, 14 had positive sputum cultures, 6 had positive blood cultures and 6 had positive urine cultures for Candida organisms. Findings on chest radiographs of most of the patients showed diffuse bronchopneumonia with confluent areas of air space consolidation. Five patients had been suspected of having Candida pneumonia and were treated empirically with amphotericin B, but none survived.

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Selected References

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  1. Andersen H. A., Fontana R. S. Transbronchoscopic lung biopsy for diffuse pulmonary diseases: technique and results in 450 cases. Chest. 1972 Aug;62(2):125–128. doi: 10.1378/chest.62.2.125. [DOI] [PubMed] [Google Scholar]
  2. BAUM G. L. The significance of Candida albicans in human sputum. N Engl J Med. 1960 Jul 14;263:70–73. doi: 10.1056/NEJM196007142630204. [DOI] [PubMed] [Google Scholar]
  3. Bode F. R., Paré J. A., Fraser R. G. Pulmonary diseases in the compromised host. A review of clinical and roentgenographic manifestations in patients with impaired host defense mechanisms. Medicine (Baltimore) 1974 Jul;53(4):255–293. doi: 10.1097/00005792-197407000-00002. [DOI] [PubMed] [Google Scholar]
  4. Bodey G. P. Fungal infections complicating acute leukemia. J Chronic Dis. 1966 Jun;19(6):667–687. doi: 10.1016/0021-9681(66)90066-x. [DOI] [PubMed] [Google Scholar]
  5. Edwards J. E., Jr, Foos R. Y., Montgomerie J. Z., Guze L. B. Ocular manifestations of Candida septicemia: review of seventy-six cases of hematogenous Candida endophthalmitis. Medicine (Baltimore) 1974 Jan;53(1):47–75. doi: 10.1097/00005792-197401000-00002. [DOI] [PubMed] [Google Scholar]
  6. Filice G., Yu B., Armstrong D. Immunodiffusion and agglutination tests for Candida in patients with neoplastic disease: inconsistent correlation of results with invasive infections. J Infect Dis. 1977 Mar;135(3):349–357. doi: 10.1093/infdis/135.3.349. [DOI] [PubMed] [Google Scholar]
  7. GOLDSTEIN E., GRIECO M. H., FINKEL G., LOURIA D. B. STUDIES ON THE PATHOGENESIS OF EXPERIMENTAL CANDIDA PARAPSILOSIS AND CANDIDA GUILLIERMONDII INFECTIONS IN MICE. J Infect Dis. 1965 Jun;115:293–302. doi: 10.1093/infdis/115.3.293. [DOI] [PubMed] [Google Scholar]
  8. Goldstein E., Hoeprich P. D. Problems in the diagnosis and treatment of systemic candidiasis. J Infect Dis. 1972 Feb;125(2):190–193. doi: 10.1093/infdis/125.2.190. [DOI] [PubMed] [Google Scholar]
  9. HALEY L. D., McCABE A. A mycologic study of 71 autopsies. Am J Clin Pathol. 1950 Jan;20(1):35–38. doi: 10.1093/ajcp/20.1.35. [DOI] [PubMed] [Google Scholar]
  10. Masur H., Rosen P. P., Armstrong D. Pulmonary disease caused by Candida species. Am J Med. 1977 Dec;63(6):914–925. doi: 10.1016/0002-9343(77)90546-0. [DOI] [PubMed] [Google Scholar]
  11. Mills S. A., Seigler H. F., Wolfe W. G. The incidence and management of pulmonary mycosis in renal allograft patients. Ann Surg. 1975 Nov;182(5):617–626. doi: 10.1097/00000658-197511000-00014. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Pillay V. K., Wilson D. M., Ing T. S., Kark R. M. Fungus infection in steroid-treated systemic lupus erythematosus. JAMA. 1968 Jul 29;205(5):261–265. [PubMed] [Google Scholar]
  13. Rifkind D., Marchioro T. L., Schneck S. A., Hill R. B., Jr Systemic fungal infections complicating renal transplantation and immunosuppressive therapy. Clinical, microbiologic, neurologic and pathologic features. Am J Med. 1967 Jul;43(1):28–38. doi: 10.1016/0002-9343(67)90146-5. [DOI] [PubMed] [Google Scholar]
  14. Taschdjian C. L., Kozinn P. J., Toni E. F. Opportunistic yeast infections, with special reference to candidiasis. Ann N Y Acad Sci. 1970 Oct 30;174(2):606–622. doi: 10.1111/j.1749-6632.1970.tb45586.x. [DOI] [PubMed] [Google Scholar]
  15. Wilson M. J., Martin D. E. Quantitative sputum culture as a means of excluding false positive reports in the routine microbiology laboratory. J Clin Pathol. 1972 Aug;25(8):697–700. doi: 10.1136/jcp.25.8.697. [DOI] [PMC free article] [PubMed] [Google Scholar]

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