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. 1990 Sep;58(3):745–757. doi: 10.1016/S0006-3495(90)82417-6

Small angle neutron scattering studies of HbA in concentrated solutions.

S Krueger 1, S H Chen 1, J Hofrichter 1, R Nossal 1
PMCID: PMC1281015  PMID: 2207261

Abstract

Differential cross-sections for neutrons scattered by normal human hemoglobin have been determined over the range of concentrations from 2 to approximately 35 weight percent. Data are compared with structure factors calculated from models of monodisperse hard spheres interacting through a screened Coulomb potential. Good agreement is noted when the volume fraction eta is adjusted during multivariate fitting of data, but the fitted value of eta is always lower than expected from the known Hb concentration of the samples. Calculations of cross-sections for polydisperse scatterers suggest that the samples may contain oligomers of the fundamental tetrameric Hb molecule.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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