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. 1990 Dec;58(6):1437–1448. doi: 10.1016/S0006-3495(90)82489-9

Direct visualization of phosphorylase-phosphorylase kinase complexes by scanning tunneling and atomic force microscopy.

R D Edstrom 1, M H Meinke 1, X R Yang 1, R Yang 1, V Elings 1, D F Evans 1
PMCID: PMC1281096  PMID: 2125841

Abstract

In skeletal muscle the activation of phosphorylase b is catalyzed by phosphorylase kinase. Both enzymes occur in vivo as part of a multienzyme complex. The two enzymes have been imaged by atomic force microscopy and the results compared to those previously found by scanning tunneling microscopy. Scanning tunneling microscopy and atomic force microscopy have been used to view complexes between the activating enzyme phosphorylase kinase and its substrate phosphorylase b. Changes in the size and shape of phosphorylase kinase were observed when it bound phosphorylase b.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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