Skip to main content
Journal of the Royal Society of Medicine logoLink to Journal of the Royal Society of Medicine
. 1994 Jun;87(6):338–341.

Anxiety and depression in migraine.

J Devlen 1
PMCID: PMC1294564  PMID: 8046705

Abstract

The present study examined the prevalence and severity of anxiety and depression among people with migraine. To obtain a spectrum of migraine experience two potentially different samples were identified: over 600 patients attending migraine clinics and 87 migraine sufferers in the general population. International Headache Society criteria were used to establish the diagnosis of migraine. Anxiety and depression were measured using the Hospital Anxiety and Depression scale and studies using this scale in other patient groups were identified for comparison. Approximately 50% of subjects experienced anxiety and 20% experienced depression, rates which were consistent across the two study groups. This prevalence of psychological morbidity is unexpectedly high and comparable to that measured in patients with other diseases. There is no evidence that it is correlated with frequency of migraine attacks. Anxiety and depression are common among people with migraine and remain largely unrecognized. Future studies should identify contributory factors.

Full text

PDF
341

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Andrews H., Barczak P., Allan R. N. Psychiatric illness in patients with inflammatory bowel disease. Gut. 1987 Dec;28(12):1600–1604. doi: 10.1136/gut.28.12.1600. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Aylard P. R., Gooding J. H., McKenna P. J., Snaith R. P. A validation study of three anxiety and depression self-assessment scales. J Psychosom Res. 1987;31(2):261–268. doi: 10.1016/0022-3999(87)90083-3. [DOI] [PubMed] [Google Scholar]
  3. Barczak P., Kane N., Andrews S., Congdon A. M., Clay J. C., Betts T. Patterns of psychiatric morbidity in a genito-urinary clinic. A validation of the Hospital Anxiety Depression scale (HAD). Br J Psychiatry. 1988 May;152:698–700. doi: 10.1192/bjp.152.5.698. [DOI] [PubMed] [Google Scholar]
  4. Brandt J., Celentano D., Stewart W., Linet M., Folstein M. F. Personality and emotional disorder in a community sample of migraine headache sufferers. Am J Psychiatry. 1990 Mar;147(3):303–308. doi: 10.1176/ajp.147.3.303. [DOI] [PubMed] [Google Scholar]
  5. Chandarana P. C., Eals M., Steingart A. B., Bellamy N., Allen S. The detection of psychiatric morbidity and associated factors in patients with rheumatoid arthritis. Can J Psychiatry. 1987 Jun;32(5):356–361. doi: 10.1177/070674378703200506. [DOI] [PubMed] [Google Scholar]
  6. Crisp A. H., Kalucy R. S., McGuinness B., Ralph P. C., Harris G. Some clinical, social and psychological characteristics of migraine subjects in the general population. Postgrad Med J. 1977 Nov;53(625):691–697. doi: 10.1136/pgmj.53.625.691. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Dowell A. C., Biran L. A. Problems in using the hospital anxiety and depression scale for screening patients in general practice. Br J Gen Pract. 1990 Jan;40(330):27–28. [PMC free article] [PubMed] [Google Scholar]
  8. Goldstein M., Chen T. C. The epidemiology of disabling headache. Adv Neurol. 1982;33:377–390. [PubMed] [Google Scholar]
  9. Hicks J. A., Jenkins J. G. The measurement of preoperative anxiety. J R Soc Med. 1988 Sep;81(9):517–519. doi: 10.1177/014107688808100907. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Hopwood P., Howell A., Maguire P. Psychiatric morbidity in patients with advanced cancer of the breast: prevalence measured by two self-rating questionnaires. Br J Cancer. 1991 Aug;64(2):349–352. doi: 10.1038/bjc.1991.304. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Hopwood P., Howell A., Maguire P. Screening for psychiatric morbidity in patients with advanced breast cancer: validation of two self-report questionnaires. Br J Cancer. 1991 Aug;64(2):353–356. doi: 10.1038/bjc.1991.305. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Jarman J., Fernandez M., Davies P. T., Glover V., Steiner T. J., Thompson C., Rose F. C., Sandler M. High incidence of endogenous depression in migraine: confirmation by tyramine test. J Neurol Neurosurg Psychiatry. 1990 Jul;53(7):573–575. doi: 10.1136/jnnp.53.7.573. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Lewis G., Wessely S. Comparison of the General Health Questionnaire and the Hospital Anxiety and Depression Scale. Br J Psychiatry. 1990 Dec;157:860–864. doi: 10.1192/bjp.157.6.860. [DOI] [PubMed] [Google Scholar]
  14. Merikangas K. R., Angst J., Isler H. Migraine and psychopathology. Results of the Zurich cohort study of young adults. Arch Gen Psychiatry. 1990 Sep;47(9):849–853. doi: 10.1001/archpsyc.1990.01810210057008. [DOI] [PubMed] [Google Scholar]
  15. Morris J., Royle G. T. Choice of surgery for early breast cancer: pre- and postoperative levels of clinical anxiety and depression in patients and their husbands. Br J Surg. 1987 Nov;74(11):1017–1019. doi: 10.1002/bjs.1800741120. [DOI] [PubMed] [Google Scholar]
  16. O'Rourke A., Lewin B., Whitecross S., Pacey W. The effects of physical exercise training and cardiac education on levels of anxiety and depression in the rehabilitation of coronary artery bypass graft patients. Int Disabil Stud. 1990 Jul-Sep;12(3):104–106. doi: 10.3109/03790799009166262. [DOI] [PubMed] [Google Scholar]
  17. Rasmussen B. K., Jensen R., Olesen J. Questionnaire versus clinical interview in the diagnosis of headache. Headache. 1991 May;31(5):290–295. doi: 10.1111/j.1526-4610.1991.hed3105290.x. [DOI] [PubMed] [Google Scholar]
  18. Rasmussen B. K., Jensen R., Schroll M., Olesen J. Epidemiology of headache in a general population--a prevalence study. J Clin Epidemiol. 1991;44(11):1147–1157. doi: 10.1016/0895-4356(91)90147-2. [DOI] [PubMed] [Google Scholar]
  19. Robertson D. A., Ray J., Diamond I., Edwards J. G. Personality profile and affective state of patients with inflammatory bowel disease. Gut. 1989 May;30(5):623–626. doi: 10.1136/gut.30.5.623. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Stewart W. F., Lipton R. B., Celentano D. D., Reed M. L. Prevalence of migraine headache in the United States. Relation to age, income, race, and other sociodemographic factors. JAMA. 1992 Jan 1;267(1):64–69. [PubMed] [Google Scholar]
  21. Wands K., Merskey H., Hachinski V. C., Fisman M., Fox H., Boniferro M. A questionnaire investigation of anxiety and depression in early dementia. J Am Geriatr Soc. 1990 May;38(5):535–538. doi: 10.1111/j.1532-5415.1990.tb02404.x. [DOI] [PubMed] [Google Scholar]
  22. Waters W. E., O'Connor P. J. Epidemiology of headache and migraine in women. J Neurol Neurosurg Psychiatry. 1971 Apr;34(2):148–153. doi: 10.1136/jnnp.34.2.148. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Wilkinson M. J., Barczak P. Psychiatric screening in general practice: comparison of the general health questionnaire and the hospital anxiety depression scale. J R Coll Gen Pract. 1988 Jul;38(312):311–313. [PMC free article] [PubMed] [Google Scholar]
  24. Zigmond A. S., Snaith R. P. The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983 Jun;67(6):361–370. doi: 10.1111/j.1600-0447.1983.tb09716.x. [DOI] [PubMed] [Google Scholar]

Articles from Journal of the Royal Society of Medicine are provided here courtesy of Royal Society of Medicine Press

RESOURCES