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Transactions of the American Ophthalmological Society logoLink to Transactions of the American Ophthalmological Society
. 1994;92:271–287.

Noncontact transscleral Nd:YAG cyclophotocoagulation: a long-term follow-up of 500 patients.

M B Shields 1, S E Shields 1
PMCID: PMC1298511  PMID: 7886867

Abstract

Long-term experience with transscleral cyclophotocoagulation in 500 patients suggests that this operation is the cyclodestructive procedure of choice. It offers a reasonable surgical option in the high-risk glaucoma population, which includes patients with neovascular glaucoma, glaucomas with active uveitis, glaucomas in aphakia or pseudophakia, and other cases in which filtering surgery has failed or is felt to have a low chance for success. Satisfactory intraocular pressure reduction was achieved in 62% of the patients with one treatment session. After one or more repeated procedures in 21% of the study group, the final intraocular pressure was below baseline in 94%, with a mean final reduction of 24 mm Hg, which was judged to be adequate for 87% of the patients. However, visual loss remains a significant postoperative complication, with some degree of reduced vision occurring in 39% of the study population. Patients with neovascular glaucoma had the greatest percentage of visual loss at 46%, compared with 34% and 38% for patients with glaucomas in pseudophakia and aphakia, respectively. While it is hard to know how many of these cases of visual loss were a direct result of the cyclophotocoagulation, the procedure should be used with caution in eyes with a potential for good central vision. Further study is needed to determine the relative indications for transcleral cyclophotocoagulation and the various operations to increase aqueous outflow in the management of patients in the high-risk glaucoma population.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bellows A. R., Grant W. M. Cyclocryotherapy of chronic open-angle glaucoma in aphakic eyes. Am J Ophthalmol. 1978 May;85(5 Pt 1):615–621. doi: 10.1016/s0002-9394(14)77093-x. [DOI] [PubMed] [Google Scholar]
  2. Blasini M., Simmons R., Shields M. B. Early tissue response to transscleral neodymium: YAG cyclophotocoagulation. Invest Ophthalmol Vis Sci. 1990 Jun;31(6):1114–1118. [PubMed] [Google Scholar]
  3. Brindley G., Shields M. B. Value and limitations of cyclocryotherapy. Graefes Arch Clin Exp Ophthalmol. 1986;224(6):545–548. doi: 10.1007/BF02154743. [DOI] [PubMed] [Google Scholar]
  4. Caprioli J., Strang S. L., Spaeth G. L., Poryzees E. H. Cyclocryotherapy in the treatment of advanced glaucoma. Ophthalmology. 1985 Jul;92(7):947–954. doi: 10.1016/s0161-6420(85)33951-9. [DOI] [PubMed] [Google Scholar]
  5. Coleman A. L., Jampel H. D., Javitt J. C., Brown A. E., Quigley H. A. Transscleral cyclophotocoagulation of human autopsy and monkey eyes. Ophthalmic Surg. 1991 Nov;22(11):638–643. [PubMed] [Google Scholar]
  6. Coleman D. J., Lizzi F. L., Driller J., Rosado A. L., Burgess S. E., Torpey J. H., Smith M. E., Silverman R. H., Yablonski M. E., Chang S. Therapeutic ultrasound in the treatment of glaucoma. II. Clinical applications. Ophthalmology. 1985 Mar;92(3):347–353. doi: 10.1016/s0161-6420(85)34028-9. [DOI] [PubMed] [Google Scholar]
  7. Echelman D. A., Nasisse M. P., Shields M. B., McGahan M. C., Fleisher L. N. Influence of exposure time on inflammatory response to neodymium:YAG cyclophotocoagulation in rabbits. Arch Ophthalmol. 1994 Jul;112(7):977–981. doi: 10.1001/archopht.1994.01090190125032. [DOI] [PubMed] [Google Scholar]
  8. Hampton C., Shields M. B., Miller K. N., Blasini M. Evaluation of a protocol for transscleral neodymium: YAG cyclophotocoagulation in one hundred patients. Ophthalmology. 1990 Jul;97(7):910–917. doi: 10.1016/s0161-6420(90)32482-x. [DOI] [PubMed] [Google Scholar]
  9. Hampton C., Shields M. B. Transscleral neodymium-YAG cyclophotocoagulation. A histologic study of human autopsy eyes. Arch Ophthalmol. 1988 Aug;106(8):1121–1123. doi: 10.1001/archopht.1988.01060140277041. [DOI] [PubMed] [Google Scholar]
  10. Noureddin B. N., Wilson-Holt N., Lavin M., Jeffrey M., Hitchings R. A. Advanced uncontrolled glaucoma. Nd:YAG cyclophotocoagulation or tube surgery. Ophthalmology. 1992 Mar;99(3):430–437. [PubMed] [Google Scholar]
  11. Prum B. E., Jr, Shields S. R., Simmons R. B., Echelman D. A., Shields M. B. The influence of exposure duration in transscleral Nd:YAG laser cyclophotocoagulation. Am J Ophthalmol. 1992 Nov 15;114(5):560–567. doi: 10.1016/s0002-9394(14)74483-6. [DOI] [PubMed] [Google Scholar]
  12. Schuman J. S., Puliafito C. A., Allingham R. R., Belcher C. D., Bellows A. R., Latina M. A., Shingleton B. J. Contact transscleral continuous wave neodymium:YAG laser cyclophotocoagulation. Ophthalmology. 1990 May;97(5):571–580. doi: 10.1016/s0161-6420(90)32550-2. [DOI] [PubMed] [Google Scholar]
  13. Sherwood M. B., Smith M. F., Driebe W. T., Jr, Stern G. A., Beneke J. A., Zam Z. S. Drainage tube implants in the treatment of glaucoma following penetrating keratoplasty. Ophthalmic Surg. 1993 Mar;24(3):185–189. [PubMed] [Google Scholar]
  14. Shields M. B., Wilkerson M. H., Echelman D. A. A comparison of two energy levels for noncontact transscleral neodymium-YAG cyclophotocoagulation. Arch Ophthalmol. 1993 Apr;111(4):484–487. doi: 10.1001/archopht.1993.01090040076034. [DOI] [PubMed] [Google Scholar]
  15. Simmons R. B., Shields M. B., Blasini M., Wilkerson M., Stern R. A. Transscleral Nd:YAG laser cyclophotocoagulation with a contact lens. Am J Ophthalmol. 1991 Dec 15;112(6):671–677. doi: 10.1016/s0002-9394(14)77273-3. [DOI] [PubMed] [Google Scholar]
  16. Skuta G. L., Beeson C. C., Higginbotham E. J., Lichter P. R., Musch D. C., Bergstrom T. J., Klein T. B., Falck F. Y., Jr Intraoperative mitomycin versus postoperative 5-fluorouracil in high-risk glaucoma filtering surgery. Ophthalmology. 1992 Mar;99(3):438–444. doi: 10.1016/s0161-6420(92)31951-7. [DOI] [PubMed] [Google Scholar]
  17. Vucicevic Z. M., Tsou K. C., Nazarian I. H., Scheie H. G., Burns W. P. A cytochemical approach to the laser coagulation of the ciliary body. Bibl Ophthalmol. 1969;79:467–478. [PubMed] [Google Scholar]

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