Abstract
We describe a method of measuring neutron scattering of aligned membranes with the momentum transfer oriented parallel or partly perpendicular to the plane of the membranes. The method obtains the complete information for the structures within fluid membranes obtainable by scattering. Data from alamethicin- and magainin-induced pores are presented. Although the in-plane scattering curves of these two peptides are similar to each other, their off-plane scattering patterns are strikingly distinct. Magainin pores exhibit intermembrane correlations.
Full Text
The Full Text of this article is available as a PDF (257.9 KB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- He K., Ludtke S. J., Worcester D. L., Huang H. W. Neutron scattering in the plane of membranes: structure of alamethicin pores. Biophys J. 1996 Jun;70(6):2659–2666. doi: 10.1016/S0006-3495(96)79835-1. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Huang H. W., Olah G. A. Uniformly oriented gramicidin channels embedded in thick monodomain lecithin multilayers. Biophys J. 1987 Jun;51(6):989–992. doi: 10.1016/S0006-3495(87)83427-6. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ludtke S. J., He K., Heller W. T., Harroun T. A., Yang L., Huang H. W. Membrane pores induced by magainin. Biochemistry. 1996 Oct 29;35(43):13723–13728. doi: 10.1021/bi9620621. [DOI] [PubMed] [Google Scholar]
- Ludtke S., He K., Huang H. Membrane thinning caused by magainin 2. Biochemistry. 1995 Dec 26;34(51):16764–16769. doi: 10.1021/bi00051a026. [DOI] [PubMed] [Google Scholar]
- Wu Y., Huang H. W., Olah G. A. Method of oriented circular dichroism. Biophys J. 1990 Apr;57(4):797–806. doi: 10.1016/S0006-3495(90)82599-6. [DOI] [PMC free article] [PubMed] [Google Scholar]