Abstract
Non dioxin‐like polychlorinated biphenyls (NDL PCBs) are persistent organic chemicals that accumulate in the environment and humans and are associated with a broad spectrum of health effects. Processing and distribution of PCBs has been prohibited in almost all industrial countries since the late 1980s but they still can be released into the environment from electrical appliances, building paint and sealants and waste sites that contain PCBs. In 2002 the European Commission prescribed a list of actions to be taken to reduce the presence of dioxins and PCBs in food and feed and Member States were recommended to monitor the situation. A total of 12,563 food and feed samples collected in the period 1995 2008 from 18 EU Member States, Iceland and Norway were retained for a detailed analysis of the occurrence of the six indicator NDL PCBs (# 28, 52, 101, 138, 153, and 180). Overall, 18.8% of the results for single congeners were below the limit of quantification (LOQ) but their distribution varied highly between food and feed groups. PCB‐153 and PCB 138 were the most commonly detected congeners. In food, the highest mean contamination level was observed in fish and fish derived products followed by eggs, milk and their products, and meat and meat products from terrestrial animals. The lowest contamination was observed in foods of plant origin. A similar pattern was observed in feed where high contamination was reported in feed containing fish derived products and comparatively very low levels in feed of plant or mineral origin. The sum of the six NDL‐PCBs was on average close to five times higher than the sum of the 12 dioxin‐like PCBs. This relationship varied across food groups and is presumably related to the origin of samples and the contamination source. Country specific clustering has been observed in several food and feed groups.
Keywords: Polychlorinated biphenyls, non dioxin‐like polychlorinated biphenyls, occurrence, food, feed
European Food Safety Authority ; Results of the monitoring of non dioxin‐like PCBs in food and feed. EFSA Journal 2010;8(7):1701. [35 pp.]. doi: 10.2903/j.efsa.2010.1701
Correspondence: datex@efsa.europa.eu
Acknowledgement: EFSA wishes to thank the EFSA's staff members Valeriu Curtui, Alessandro Carletti, Pietro Ferrari and Stefan Fabiansson for the support provided to this EFSA scientific output. Special thanks to Peter Fürst, and Alexander Kotz for their valuable comments.
Approval date: 22 July 2010
Published date: 30 July 2010
Question number: EFSA‐Q‐2010‐00970
On request from: EFSA
References
- AFSSA (Agence Française de Sécurité Sanitaire des Aliments) (2009). Opinion of the French Food Safety Agency regarding the determination of threshold values for NDL‐PCBs as a tool for assessing the risk of PCB contamination in freshwater and marine fish. AFSSA Request No. 2009‐SA‐0241. www.afssa.fr/Documents/PASER2009sa0241EN.pdf.
- AFSSA (Agence Française de Sécurité Sanitaire des Aliments) (2010). Opinion of the French food Safety Agency on interpreting the health impact of PCB concentration levels in the French population. AFSSA – Request No. 2008‐SA‐0053. www.afssa.fr/Documents/RCCP2008sa0053EN.pdf.
- Arnich N, Tard A, Leblanc J‐C, Le Bizec B, Narbonne J‐F, Maximilien R (2009). Dietary intake of non‐dioxin‐like PCBs) in France, impact on maximum levels in some foodstuffs. Regulatory Pharmacology and Toxicology 54: 287–293. [DOI] [PubMed] [Google Scholar]
- ATSDR (Agency for Toxic Substances and Disease Registry) (2000). Toxicological profile for Polychlorinated biphenyls (PCBs). Agency for Toxic Substances and Disease Registry, U.S. Department Of Health And Human Services. www.atsdr.cdc.gov/toxprofiles/tp17.pdf. [PubMed] [Google Scholar]
- Baars AJ, Bakker MI, Baumann RA, Boon PE, Freijer JI, Hoogenboom LAP, Hoogerbrugge R, Van Klaveren JD, Liem AKD, Traag WA, De Vries J (2004). Dioxins, dioxin‐like PCBs and non‐dioxin‐like PCBs in foodstuffs: occurrence and dietary intake in the Netherlands. Toxicology Letters 151: 51–61. [DOI] [PubMed] [Google Scholar]
- Ballschmiter K, and Zell M, (1980). Analysis of polychlorinated biphenyls (PCB) by glass capillary gas chromatography. Fresenius' Zeitschrift für Analytische Chemie 302: 20–31. [Google Scholar]
- Breivik K, Sweetman A, Pacyna JM, Jones KC (2002). Towards a global historical emission inventory for selected PCB congeners ‐ a mass balance approach 1. Global production and consumption”. The Science of the Total Environment 290: 181–198. [DOI] [PubMed] [Google Scholar]
- BfR (Bundesinstitut für Risikobewertung) (2006). Gesundheitliche Bewertung Nr. 041/2006 des BfR vom 1. Juni 2006,EU‐Höchstgehalte für Dioxine und dioxinähnliche PCB in Fisch schützen Vielverzehrer von fetthaltigem Fisch nicht immer ausreichend”. www.bfr.bund.de/cm/208/eu_hoechstgehalte_fuer_dioxine_und_dioxinaehnliche_pcb_in_fisch.pdf.
- Dobson S, Van Esch GJ. (1993). Environmental Health Criteria 140: Polychlorinated Biphenyls and Terphenyls, World Health Organisation, International Programme on Chemical Safety, Geneva, Switzerland. [Google Scholar]
- EC (European Commission) , 2002. Commission Recommendation 2002/201/EC of 4 March 2002 on the reduction of the presence of dioxins, furans and PCBs in feedingstuffs and foodstuffs. Official Journal of the European Union, L 67, 9.3.2002, 69–73. [Google Scholar]
- EC (European Commission) , 2004. Commission Recommendation 2004/704/EC of 11 October 2004 on the monitoring of background levels of dioxins and dioxin‐like PCBs in feedingstuffs. Official Journal of the European Union, L 321, 22.10.2004, 38–44. [Google Scholar]
- EC (European Commission) , 2004. Commission Recommendation 2004/705/EC of 11 October 2004 on the monitoring of background levels of dioxins and dioxin‐like PCBs in foodstuffs. Official Journal of the European Union, L 321, 22.10.2004, 45–52. [Google Scholar]
- EC (European Commission) , 2006. Commission Directive 2006/13/EC of 3 February 2006 amending Annexes I and II to Directive 2002/32/EC of the European Parliament and of the Council on undesirable substances in animal feed as regards dioxins and dioxin‐like PCBs. Official Journal of the European Union, L 32, 4.2.2006, 44–53. [Google Scholar]
- EC (European Commission) , 2006. Commission Recommendation 2006/794/EC of 16 November 2006 on the monitoring of background levels of dioxins, dioxin‐like PCBs and non‐dioxin‐like PCBs in foodstuffs. Official Journal of the European Union, L 322, 22.11.2006, 24–31. [Google Scholar]
- EC (European Commission) , 2006. Commission Regulation (EC) No 1881/2006 of 19 December 2006 setting maximum levels for certain contaminants in foodstuffs. Official Journal of the European Union, L 364, 20.12.2006, 5–24. [Google Scholar]
- EC (European Commission) , 2006. Commission Regulation (EC) No 1883/2006 of 19 December 2006 laying down methods of sampling and analysis for the official control of levels of dioxins and dioxin‐like PCBs in certain foodstuffs. Official Journal of the European Union, L 364, 21.12.2006, 32–43. [Google Scholar]
- EC (European Commission) , 2009. Commission Regulation (EC) No 152/2009 of 27 January 2009 laying down the methods of sampling and analysis for the official control of feed. Official Journal of the European Union, L 54, 26.2.2009, 1–130. [Google Scholar]
- EFSA (European Food Safety Agency) (2005). Opinion of the Scientific Panel on Contaminants in the Food chain on a Request from the Commission related to the Presence of non dioxin‐like Polychlorinated Biphenyls (PCB) in Feed and Food, 284, 1–137. [Google Scholar]
- EFSA (European Food Safety Agency) (2010). Results of the monitoring of dioxin levels in food and feed. EFSA Journal 2010; 8(3):1385 [35 pp]. [DOI] [PMC free article] [PubMed] [Google Scholar]
- EPA (US Environmental Protection Agency) (1996). PCBs: Cancer Dose‐Response Assessment and Application to Environmental Mixtures. EPA/600/P‐ 96,/ 001F. www.epa.gov/epawaste/hazard/tsd/pcbs/pubs/pcb.pdf.
- EPA (US Environmental Protection Agency) (2003). Non‐dioxin‐like PCBs: effects and consideration in ecological risk assessment. www.epa.gov/oswer/riskassessment/pdf/1340‐erasc‐003.pdf.
- EPC (European Parliament and Council of the European Union) , 2002. Directive 2002/32/EC of the European Parliament and of the Council of 7 May 2002 on undesirable substances in animal feed. Official Journal of the European Union, L 140, 30.5.2002, 10–21. [Google Scholar]
- EPC (European Parliament and Council of the European Union) , 2004. Regulation (EC) No 882/2004 of the European Parliament and of the Council of 29 April 2004 on official controls performed to ensure the verification of compliance with feed and food law, animal health and animal welfare rules. Official Journal of the European Union, L 165, 30.4.2004, p.6–135. [Google Scholar]
- European Union Reference Laboratory (EU‐RL) for Dioxins and PCBs in Feed and Food (2009). Analytical requirements for determination of non dioxin‐like PCBs in food (PCB # 28, 52, 101, 138, 153, 180). www.crl‐freiburg.eu/dioxin/methods.html#ndl.
- Jenssen S. (1966) Report of a new chemical hazard, New Scientist, 32, 612. [Google Scholar]
- Jursa S, Chovancová J, Petrík J, Loksa J. (2006). Dioxin‐like and non‐dioxin‐like PCBs in human serum of Slovak population. Chemosphere, 64(4):686–691. [DOI] [PubMed] [Google Scholar]
- SAS Institute (1999). SAS Online Doc1, Version 8. Cary, NC: SAS Institute Inc. [Google Scholar]
- Safe S, Bandiera S, Sawyer T, Robertson L, Safe L, Parkinson A, Thomas PE, Ryan DE, Reik LM, Levin W. (1985). PCBs: structure‐function relationships and mechanism of action. Environ. Health Perspect. 60: 47–56. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Safe S. (1990). Polichlorinated biphenyls (PCB), dibenzo‐para‐dioxins (PCDDs), dibenzofurans (PCDFs), and related compounds: environmental and mechanistic considerations which suport the development of TEF. Critical Rev. Toxicol 21:51–58. [DOI] [PubMed] [Google Scholar]
- SCAN (Scientific Committee on Animal Nutrition) , (2000). Opinion on the, Dioxin contamination of feedingstuffs and their contribution to the contamination of food of animal origin” (Adopted on 06 November 2000). europa.eu.int/comm/food/fs/sc/scan/out55_en.pdf.
- SCF (Scientific Committee on Food) , (2000). Opinion on the risk assessment of dioxins and dioxin‐like PCB in food (adopted on 22 November 2000) europa.eu.int/comm/food/fs/sc/scf/out78_en.pdf.
- Schwind K‐H, Jira W, Karl H, Ruoff U, Daenicke S. (2009). Statuserhebung zu Dioxinen und PCB in Futter‐ und vom Tier stammenden Lebensmitteln. Forschungsprojekt des Bundesministeriums für Ernährung, Landwirtschaft und Verbraucherschutz und des Max‐Rubner‐Instituts zur Durchführung einer nationalen Statuserhebung von Dioxin‐ und dioxinähnlichen PCB‐Verbindungen in Futter‐ und vom Tier stammenden Lebensmitteln. Schriftenreihe des Bundesministeriums für Ernährung, Landwirtschaft und Verbraucherschutz: Reihe A, Angewandte Wissenschaft; 522 [179 pp.]. [Google Scholar]
- Turyk M, Anderson HA, Hanrahan LP, Falk C, Steenport DN, Needham LL, Patterson DG Jr, Freels S, Persky V; Great Lakes Consortium (2006). Relationship of serum levels of individual PCB, dioxin, and furan congeners and DDE with Great Lakes sport‐caught fish consumption. Environ Res, 100:173–183. [DOI] [PubMed] [Google Scholar]
- UNEP (United Nations Environment Programme) (1993). Guidelines for the Identification of PCBs and Materials Containing PCBs. Prepared by UNEP Chemicals. www.chem.unep.ch/pops/pdf/PCBident/pcbid1.pdf.
- USDE (U.S. Department of Energy) (1994). Disposal Requirements for PCB Waste. Office of Environmental Guidance. homer.ornl.gov/nuclearsafety/env/guidance/tsca/pcb‐disp.pdf. [Google Scholar]
- WHO (World Health Organization) (1978). International Agency for Research on Cancer, IARC monographs on the evaluation of carcinogenic risks to humans, Polychlorinated biphenyls and Polybrominated biphenyls, Summary of Data Reported and Evaluation Vol. 18, monographs.iarc.fr/ENG/Monographs/vol18/volume18.pdf. [Google Scholar]
- WHO (World Health Organization) (2001). WHO Consultation on Risk Assessment of Non‐dioxin‐like PCBs. Geneva, Switzerland. www.who.int/pcs/docs/consultation_%20pcb.htm. [Google Scholar]
- WHO (World Health Organization) (2003). Polychlorinated Biphenyls: Human Health Aspects. Concise International Chemical Assessment Document 55. www.who.int/ipcs/publications/cicad/en/cicad55.pdf.
