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. 1972;70:577–614.

The ocular manifestations of congenital rubella.

S M Wolff
PMCID: PMC1310470  PMID: 4197454

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Alfano J. E. Ocular aspects of the maternal rubella syndrome. Trans Am Acad Ophthalmol Otolaryngol. 1966 Mar-Apr;70(2):235–266. [PubMed] [Google Scholar]
  2. Alford C. A., Jr Studies on antibody in congenital rubella infections. I. Physicochemical and immunologic investigations of rubella neutralizing antibody. Am J Dis Child. 1965 Oct;110(4):455–463. doi: 10.1001/archpedi.1965.02090030475019. [DOI] [PubMed] [Google Scholar]
  3. Boniuk M., Zimmerman L. E. Ocular pathology in the rubella syndrome. Arch Ophthalmol. 1967 Apr;77(4):455–473. doi: 10.1001/archopht.1967.00980020457008. [DOI] [PubMed] [Google Scholar]
  4. Boniuk V., Boniuk M. The incidence of phthisis bulbas a complication of cataract surgery in the congenital rubella syndrome. Trans Am Acad Ophthalmol Otolaryngol. 1970 Mar-Apr;74(2):360–368. [PubMed] [Google Scholar]
  5. CORDES F. C. Cataract formation in the human embryo after rubella. Arch Ophthal. 1949 Nov;42(5):596-605, illust. doi: 10.1001/archopht.1949.00900050606009. [DOI] [PubMed] [Google Scholar]
  6. CORDES F. C. Evaluation of the surgery of congenital cataracts. AMA Arch Ophthalmol. 1951 Aug;46(2):132–144. doi: 10.1001/archopht.1951.01700020138002. [DOI] [PubMed] [Google Scholar]
  7. CORDES F. C. Linear extraction in congenital cataract surgery. Am J Ophthalmol. 1961 Sep;52:355–360. doi: 10.1016/0002-9394(61)90733-4. [DOI] [PubMed] [Google Scholar]
  8. Chang T. H., Moorhead P. S., Boué J. G., Plotkin S. A., Hoskins J. M. Chromosome studies of human cells infected in utero and in vitro with rubella virus. Proc Soc Exp Biol Med. 1966 May;122(1):236–243. doi: 10.3181/00379727-122-31099. [DOI] [PubMed] [Google Scholar]
  9. Collis W. J., Cohen D. N. Rubella retinopathy. A progressive disorder. Arch Ophthalmol. 1970 Jul;84(1):33–35. doi: 10.1001/archopht.1970.00990040035009. [DOI] [PubMed] [Google Scholar]
  10. Cooper L. Z., Green R. H., Krugman S., Giles J. P., Mirick G. S. Neonatal thrombocytopenic purpura and other manifestations of rubella contracted in utero. Am J Dis Child. 1965 Oct;110(4):416–427. doi: 10.1001/archpedi.1965.02090030436011. [DOI] [PubMed] [Google Scholar]
  11. Desmyter J. Serological diagnosis of rubella. Br Med J. 1970 Oct 10;4(5727):119–119. doi: 10.1136/bmj.4.5727.119-b. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Doege T. C., Kim K. S. Studies of rubella and its prevention with immune globulin. JAMA. 1967 May 15;200(7):584–590. [PubMed] [Google Scholar]
  13. Dudgeon J. A. Teratogenic effect of rubella virus. Proc R Soc Med. 1970 Dec;63(12):1254–1257. [PMC free article] [PubMed] [Google Scholar]
  14. FRANCESCHETTI A., DIETERLE P., SCHWARZ A. Retinite pigmentaire à virus; relation entre tableau clinique et électrorétinogramme (ERG). Ophthalmologica. 1958 May-Jun;135(5-6):545–554. doi: 10.1159/000303350. [DOI] [PubMed] [Google Scholar]
  15. Forrest J. M., Menser M. A. Congenital rubella in schoolchildren and adolescents. Arch Dis Child. 1970 Feb;45(239):63–69. doi: 10.1136/adc.45.239.63. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. GUIBOR G. P. Some eye defects seen in cerebral palsy, with some statistics. Am J Phys Med. 1953 Dec;32(6):342–347. [PubMed] [Google Scholar]
  17. Geltzer A. I., Guber D., Sears M. L. Ocular manifestations of the 1964-65 rubella epidemic. Am J Ophthalmol. 1967 Feb;63(2):221–229. doi: 10.1016/0002-9394(67)91541-3. [DOI] [PubMed] [Google Scholar]
  18. Hancock M. P., Huntley C. C., Sever J. L. Congenital rubella syndrome with immunoglobulin disorder. J Pediatr. 1968 May;72(5):636–645. doi: 10.1016/s0022-3476(68)80006-x. [DOI] [PubMed] [Google Scholar]
  19. Hardy J. B., Sever J. L., Gilkeson M. R. Declining antibody titers in children with congenital rubella. J Pediatr. 1969 Aug;75(2):213–220. doi: 10.1016/s0022-3476(69)80391-4. [DOI] [PubMed] [Google Scholar]
  20. Hertzberg R. Ocular defects in congenital rubella. Med J Aust. 1969 Mar 15;1(11):594–595. doi: 10.5694/j.1326-5377.1969.tb92309.x. [DOI] [PubMed] [Google Scholar]
  21. Hertzberg R. Twenty-five-year follow-up of ocular defects in congenital rubella. Am J Ophthalmol. 1968 Aug;66(2):269–271. doi: 10.1016/0002-9394(68)92072-2. [DOI] [PubMed] [Google Scholar]
  22. Ikui H., Oshima K., Kano M., Inomata H., Ueda K. [Congenital rubella syndrome in Okinawa, with special reference to its ocular manifestations]. Nippon Ganka Gakkai Zasshi. 1969 Aug;73(8):1083–1093. [PubMed] [Google Scholar]
  23. Kenrick K. G., Slinn R. F., Dorman D. C., Menser M. A. Immunoglobulins and rubella-virus antibodies in adults with congenital rubella. Lancet. 1968 Mar 16;1(7542):548–551. doi: 10.1016/s0140-6736(68)92828-6. [DOI] [PubMed] [Google Scholar]
  24. Krause A. C. Congenital Cataracts Following Rubella in Pregnancy. Ann Surg. 1945 Dec;122(6):1049–1055. [PMC free article] [PubMed] [Google Scholar]
  25. Krill A. E. The retinal disease of rubella. Arch Ophthalmol. 1967 Apr;77(4):445–449. doi: 10.1001/archopht.1967.00980020447006. [DOI] [PubMed] [Google Scholar]
  26. LANCET M. [Comparison of pheylbutazone and P.H. 203 in the treatment of superficial puerperal phlebitis]. Harefuah. 1961 May 1;60:289–291. [PubMed] [Google Scholar]
  27. Menser M. A., Dods L., Harley J. D. A twenty-five-year follow-up of congenital rubella. Lancet. 1967 Dec 23;2(7530):1347–1350. doi: 10.1016/s0140-6736(67)90932-4. [DOI] [PubMed] [Google Scholar]
  28. Menser M. A., Harley J. D., Hertzberg R., Dorman D. C., Murphy A. M. Persistence of virus in lens for three years after prenatal rubella. Lancet. 1967 Aug 19;2(7512):387–388. doi: 10.1016/s0140-6736(67)92007-7. [DOI] [PubMed] [Google Scholar]
  29. Menser M. A., Slinn R. F., Forrest J. M., Nowak M. J., Dorman D. C. Rubella viruria in a 29-year-old woman with congenital rubella. Lancet. 1971 Oct 9;2(7728):797–798. doi: 10.1016/s0140-6736(71)92744-9. [DOI] [PubMed] [Google Scholar]
  30. Merigan T. C. Interferons of mice and men. N Engl J Med. 1967 Apr 20;276(16):913–920. doi: 10.1056/NEJM196704202761608. [DOI] [PubMed] [Google Scholar]
  31. Michaels R. H. Immunologic aspects of congenital rubella. Pediatrics. 1969 Mar;43(3):339–350. [PubMed] [Google Scholar]
  32. Murphy A. M., Reid R. R., Pollard I., Gillespie A. M., Dorman D. C., Menser M. A., Harley J. D., Hertzberg R. Rubella cataracts. Further clinical and virologic observations. Am J Ophthalmol. 1967 Dec;64(6):1109–1119. [PubMed] [Google Scholar]
  33. NEVA F. A., WELLER T. H. RUBELLA INTERFERON AND FACTORS INFLUENCING THE INDIRECT NEUTRALIZATION TEST FOR RUBELLA ANTIBODY. J Immunol. 1964 Sep;93:466–473. [PubMed] [Google Scholar]
  34. Naeye R. L., Blanc W. Pathogenesis of congenital rubella. JAMA. 1965 Dec 20;194(12):1277–1283. [PubMed] [Google Scholar]
  35. Nusbacher J., Hirschhorn K., Cooper L. Z. Chromosomal abnormalities in congenital rubella. N Engl J Med. 1967 Jun 22;276(25):1409–1413. doi: 10.1056/NEJM196706222762505. [DOI] [PubMed] [Google Scholar]
  36. Olson G. B., South M. A., Good R. A. Phytohaemagglutinin unresponsiveness of lymphocytes from babies with congenital rubella. Nature. 1967 May 13;214(5089):695–696. doi: 10.1038/214695a0. [DOI] [PubMed] [Google Scholar]
  37. PHILLIPS C. A., BEHBEHANI A. M., JOHNSON L. W., MELNICK J. L. ISOLATION OF RUBELLA VIRUS: AN EPIDEMIC CHARACTERIZED BY RASH AND ARTHRITIS. JAMA. 1965 Feb 22;191:615–618. doi: 10.1001/jama.1965.03080080005001. [DOI] [PubMed] [Google Scholar]
  38. Parks M. M., Hiles D. A. Management of infantile cataracts. Am J Ophthalmol. 1967 Jan;63(1):10–19. doi: 10.1016/0002-9394(67)90575-2. [DOI] [PubMed] [Google Scholar]
  39. Plotkin S. A., Vaheri A. Human fibroblasts infected with rubella virus produce a growth inhibitor. Science. 1967 May 5;156(3775):659–661. doi: 10.1126/science.156.3775.659. [DOI] [PubMed] [Google Scholar]
  40. Rawls W. E., Desmyter J., Melnick J. L. Serologic diagnosis and fetal involvement in maternal rubella. Criteria for abortion. JAMA. 1968 Feb 26;203(9):627–631. [PubMed] [Google Scholar]
  41. Reid R. R., Murphy A. M. Isolation of rubella virus from congenital cataracts removed at operation. Med J Aust. 1966 Mar 26;1(13):540–542. doi: 10.5694/j.1326-5377.1966.tb72577.x. [DOI] [PubMed] [Google Scholar]
  42. Ryan S. J., Blanton F. M., von Noorden G. K. Surgery of congenital cataract. Am J Ophthalmol. 1965 Oct;60(4):583–587. doi: 10.1016/0002-9394(65)92243-9. [DOI] [PubMed] [Google Scholar]
  43. Ryan S. J., Von Noorden G. K. Further observations on the aspiration technique in cataract surgery. Am J Ophthalmol. 1971 Mar;71(3):626–630. doi: 10.1016/0002-9394(71)90426-0. [DOI] [PubMed] [Google Scholar]
  44. SEVER J. L., BRODY J. A., SCHIFF G. M., MCALISTER R., CUTTING R. RUBELLA EPIDEMIC ON ST. PAUL ISLAND IN THE PRIBILOFS, 1963. II. CLINICAL AND LABORATORY FINDINGS FOR THE INTENSIVE STUDY POPULATION. JAMA. 1965 Feb 22;191:624–626. doi: 10.1001/jama.1965.03080080014003. [DOI] [PubMed] [Google Scholar]
  45. Scheie H. G., Rubenstein R. A., Kent R. B. Aspiration of congenital or soft cataracts: further experience. Am J Ophthalmol. 1967 Jan;63(1):3–8. doi: 10.1016/0002-9394(67)90573-9. [DOI] [PubMed] [Google Scholar]
  46. Sears M. L. Congenital glaucoma in neonatal rubella. Br J Ophthalmol. 1967 Nov;51(11):744–748. doi: 10.1136/bjo.51.11.744. [DOI] [PMC free article] [PubMed] [Google Scholar]
  47. Sever J. L., Nelson K. B., Gilkeson M. R. Rubella epidemic, 1964: effect on 6,000 pregnancies. Am J Dis Child. 1965 Oct;110(4):395–407. doi: 10.1001/archpedi.1965.02090030415009. [DOI] [PubMed] [Google Scholar]
  48. Sever J., White L. R. Intrauterine viral infections. Annu Rev Med. 1968;19:471–486. doi: 10.1146/annurev.me.19.020168.002351. [DOI] [PubMed] [Google Scholar]
  49. Sterzl J., Silverstein A. M. Developmental aspects of immunity. Adv Immunol. 1967;6:337–459. doi: 10.1016/s0065-2776(08)60525-8. [DOI] [PubMed] [Google Scholar]
  50. Vaheri A., Vesikari T., Oker-Blom N., Seppala M., Veronelli J., Robbins F. C., Parkman P. D. Transmission of attenuated rubella vaccines to the human fetus. A preliminary report. Am J Dis Child. 1969 Aug;118(2):243–246. doi: 10.1001/archpedi.1969.02100040245016. [DOI] [PubMed] [Google Scholar]
  51. Weiss D. I., Cooper L. Z., Green R. H. Infantile glaucoma. A manifestation of congenital rubella. JAMA. 1966 Feb 28;195(9):725–727. doi: 10.1001/jama.195.9.725. [DOI] [PubMed] [Google Scholar]
  52. Yanoff M., Schaffer D. B., Scheie H. G. Rubella ocular syndrome. Clinical significance of viral and pathologic studies. Trans Am Acad Ophthalmol Otolaryngol. 1968 Nov-Dec;72(6):896–902. [PubMed] [Google Scholar]
  53. ZIMMERMAN L. E. PATHOGENESIS OF RUBELLA CATARACT. GREGG'S SYNDROME. Arch Ophthalmol. 1965 Jun;73:761–763. [PubMed] [Google Scholar]
  54. Zimmerman L. E. Histopathologic basis for ocular manifestations of congenital rubella syndrome. Am J Ophthalmol. 1968 Jun;65(6):837–862. doi: 10.1016/0002-9394(68)92210-1. [DOI] [PubMed] [Google Scholar]

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