Abstract
When dexamethasone was administered intramuscularly to Hereford calves at the time of inoculation with Eimeria zurnii and E. bovis, there was no apparent effect on the resulting infection. Medication at the time of appearance of the clinical signs caused sufficient aggravation of the disease to result in the death of the animals. Administration of the drug after subsidence of the clinical signs did not cause a clinical relapse, but resulted in prolonged oocyst discharge in the feces. Treatment of uninoculated normal calves with dexamethasone caused a brief period of increased oocyst discharge without clinical signs.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- Callow L. L., Parker R. J. Cortisone-induced relapses in Babesia argentina infections of cattle. Aust Vet J. 1969 Mar;45(3):103–104. doi: 10.1111/j.1751-0813.1969.tb01888.x. [DOI] [PubMed] [Google Scholar]
- Campbell W. C. Effect of anti-inflammatory agents on spontaneous cure of Trichinella and Trichuris in mice. J Parasitol. 1968 Jun;54(3):452–456. [PubMed] [Google Scholar]
- Long P. L. Development (schizogony) of Eimeria tenella in the liver of chickens treated with corticosteroid. Nature. 1970 Jan 17;225(5229):290–291. doi: 10.1038/225290a0. [DOI] [PubMed] [Google Scholar]
- McLoughlin D. K. The influence of dexamethasone on attempts to transmit Eimeria meleagrimitis to chickens and E. tenella to turkeys. J Protozool. 1969 Feb;16(1):145–148. doi: 10.1111/j.1550-7408.1969.tb02246.x. [DOI] [PubMed] [Google Scholar]
- Michel J. F., Sinclair I. J. The effect of cortisone on the worm burdens of calves infected daily with Ostertagia ostertagi. Parasitology. 1969 Aug;59(3):691–708. doi: 10.1017/s0031182000031218. [DOI] [PubMed] [Google Scholar]
- Michel J. F. The effect of cortisone on populations of Ostertagia ostertagi of uniform age. Br Vet J. 1969 Dec;125(12):617–621. doi: 10.1016/s0007-1935(17)48608-8. [DOI] [PubMed] [Google Scholar]
- NICOL T., DRUCE C. Effect of dexamethasone on the phagocytic activity of the reticulo-endothelial system. Nature. 1961 Apr 1;190:91–92. doi: 10.1038/190091a0. [DOI] [PubMed] [Google Scholar]
- Niilo L. Experimental infection of newborn calves with coccidia and reinfection after weaning. Can J Comp Med. 1969 Oct;33(4):287–291. [PMC free article] [PubMed] [Google Scholar]
- Patton C. L., Clark D. T. Trypanosoma lewisi infections in normal rats and in rats treated with dexamethasone. J Protozool. 1968 Feb;15(1):31–35. doi: 10.1111/j.1550-7408.1968.tb02086.x. [DOI] [PubMed] [Google Scholar]
- RISTIC M., WHITE F. H., GREEN J. H., SANDERS D. A. Effect of cortisone on the mechanism of Anaplasma immunity in experimentally infected calves. I. Hematological and immunoserological studies. Am J Vet Res. 1958 Jan;19(70):37–43. [PubMed] [Google Scholar]