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Canadian Journal of Comparative Medicine logoLink to Canadian Journal of Comparative Medicine
. 1974 Oct;38(4):398–405.

Lesions of the Central Nervous System Induced in Nonhuman Primates by Live Influenza Viruses

G Lussier 1, A Boudreault 1, V Pavilanis 1, E DiFranco 1
PMCID: PMC1319841  PMID: 4279758

Abstract

Intracerebral and intraspinal inoculations of non-neuropathic and neuropathic strains of influenza virus into rhesus, patas and cercopithecus monkeys resulted in an acute focal ependymitis, choroiditis and meningitis followed by focal ependymal denuding without parenchymal involvement. Aqueductal stenosis and moderate hydrocephalus developed in two animals as sequelae of ependymal cell loss.

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Selected References

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