Abstract
The ability of bovine tongue origin foot-and-mouth disease virus serotypes A, O and C to replicate in seven different types of cell cultures was studied. Primary and secondary calf thyroid cells were equivalent in susceptibility to bovine kidney cell cultures passaged up to five times. Calf thyroid cells lost their susceptibility after two passages. Cryopreserved bovine kidney cell cultures passaged three and four times were equivalent in susceptibility to sensitive calf thyroid and bovine kidney cells. Susceptibility to foot-and-mouth disease virus serotype C was most variable among the cells tested. Lamb testicle and porcine kidney cells were susceptible to foot-and-mouth disease virus while goat and calf testicle and calf lung cells were refractory.
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Selected References
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- BACHRACH H. L., HESS W. R., CALLIS J. J. Foot-and-mouth disease virus: its growth and cytopathogenicity in tissue culture. Science. 1955 Dec 30;122(3183):1269–1270. doi: 10.1126/science.122.3183.1269. [DOI] [PubMed] [Google Scholar]
- Cottral G. E., Patty R. E., Gailiunas P., Scott F. W. Sensitivity of cell cultures, cattle, mice, and guinea-pigs for detection of nineteen foot-and-mouth disease viruses. Bull Off Int Epizoot. 1965 Sep-Oct;63(9):1607–1625. [PubMed] [Google Scholar]
- Cowan K. M., Graves J. H. A third antigenic component associated with foot-and-mouth disease infection. Virology. 1966 Nov;30(3):528–540. doi: 10.1016/0042-6822(66)90128-0. [DOI] [PubMed] [Google Scholar]
- HESS W. R., MAY H. J., PATTY R. E. Serial cultures of lamb testicular cells and their use in virus studies. Am J Vet Res. 1963 Jan;24:59–64. [PubMed] [Google Scholar]
- Snowdon W. A. Growth of foot-and mouth disease virus in monolayer cultures of calf thyroid cells. Nature. 1966 Jun 4;210(5040):1079–1080. doi: 10.1038/2101079a0. [DOI] [PubMed] [Google Scholar]
- Sutmoller P., McVicar J. W., Cottral G. E. The epizootiological importance of foot-and-mouth disease carriers. I. Experimentally produced foot-and-mouth disease carriers in susceptible and immune cattle. Arch Gesamte Virusforsch. 1968;23(3):227–235. doi: 10.1007/BF01241895. [DOI] [PubMed] [Google Scholar]