Abstract
Pulsed-gradient 31P NMR was used to measure the diffusion rates of phosphorus compounds in aqueous solution and in living muscles. The diffusion rates of creatine phosphate and inorganic phosphate in intact frog muscle cells were reduced by a factor of approximately 2 from those in aqueous solution, which suggests that the apparent intracellular viscosity is approximately 2 times larger than in aqueous solution.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bunch W. H., Kallsen G. Rate of intracellular diffusion as measured in barnacle muscle. Science. 1969 Jun 6;164(3884):1178–1179. doi: 10.1126/science.164.3884.1178. [DOI] [PubMed] [Google Scholar]
- Cleveland G. G., Chang D. C., Hazlewood C. F., Rorschach H. E. Nuclear magnetic resonance measurement of skeletal muscle: anisotrophy of the diffusion coefficient of the intracellular water. Biophys J. 1976 Sep;16(9):1043–1053. doi: 10.1016/S0006-3495(76)85754-2. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Cooper R. L., Chang D. B., Young A. C., Martin C. J., Ancker-Johnson D. Restricted diffusion in biophysical systems. Experiment. Biophys J. 1974 Mar;14(3):161–177. doi: 10.1016/s0006-3495(74)85904-7. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kushmerick M. J., Podolsky R. J. Ionic mobility in muscle cells. Science. 1969 Dec 5;166(3910):1297–1298. doi: 10.1126/science.166.3910.1297. [DOI] [PubMed] [Google Scholar]
- Tanner J. E. Self diffusion of water in frog muscle. Biophys J. 1979 Oct;28(1):107–116. doi: 10.1016/S0006-3495(79)85162-0. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Yoshizaki K. Phosphorus nuclear magnetic resonance studies of phosphorus metabolites in frog muscle. J Biochem. 1978 Jul;84(1):11–18. doi: 10.1093/oxfordjournals.jbchem.a132098. [DOI] [PubMed] [Google Scholar]