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. 1988 Feb;53(2):261–269. doi: 10.1016/S0006-3495(88)83087-X

Analysis of the factors that influence the C=N stretching frequency of polyene Schiff bases. Implications for bacteriorhodopsin and rhodopsin.

H S Gilson 1, B H Honig 1, A Croteau 1, G Zarrilli 1, K Nakanishi 1
PMCID: PMC1330146  PMID: 3345334

Abstract

In this study quantum mechanical calculations of force constants and normal mode analysis are used to elucidate the factors that influence the C=C and C=N stretching frequencies in polyenes and in protonated Schiff bases. The C=N stretching frequency is found to depend on both the C=N stretching force constant and the C=N-H bending force constant. Due to the contributions of these two modes, the C=N stretching frequency is particularly sensitive to the magnitude of the Schiff base counterion interactions and to the hydrogen bonding environment of the Schiff base nitrogen. Models for chromophore-protein interactions in the retinal binding site and for the photochemical transformations of bacteriorhodopsin and rhodopsin are evaluated in light of these results.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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