Skip to main content
The Journal of Physiology logoLink to The Journal of Physiology
. 1972 Apr;222(2):335–343. doi: 10.1113/jphysiol.1972.sp009800

The effect of efferent discharges in renal nerves on the activity of arterial mechanoreceptors in the kidney in rabbit

Akira Niijima
PMCID: PMC1331384  PMID: 5033467

Abstract

1. The effect of sympathetic efferent flow in renal nerves on afferent discharges from renal arterial mechanoreceptors was observed in dissected filaments of renal nerves in the rabbit.

2. An increase in afferent discharge rate was observed after renal nerve stimulation.

3. Perfusate accumulated during renal nerve stimulation in an isolated kidney preparation showed a vasoconstrictor effect on blood vessels in rabbit ear.

4. Infusion of a small amount of (±)-noradrenaline increased afferent discharge rate.

5. Modification of blood pressure levels by chemical means modified renal afferent discharge rate.

6. It is suggested that there is an efferent control mechanism on the activity of renal arterial mechanoreceptors by a vasomotor reflex.

Full text

PDF
337

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Aukland K. Effect of adrenaline, noradrenaline, angiotensin and renal nerve stimulation on intrarenal distribution of blood flow in dogs. Acta Physiol Scand. 1968 Apr;72(4):498–509. doi: 10.1111/j.1748-1716.1968.tb03874.x. [DOI] [PubMed] [Google Scholar]
  2. BLOCK M. A., WAKIM K. G., MANN F. C. Circulation through kidney during stimulation of the renal nerves. Am J Physiol. 1952 Jun;169(3):659–669. doi: 10.1152/ajplegacy.1952.169.3.659. [DOI] [PubMed] [Google Scholar]
  3. HIX E. L. Uretero-renal reflex facilitating renal vasoconstrictor responses to emotional stress. Am J Physiol. 1958 Jan;192(1):191–197. doi: 10.1152/ajplegacy.1957.192.1.191. [DOI] [PubMed] [Google Scholar]
  4. HOUCK C. R., MOORE A. W., COCHRAN N. H., CANADA A. Alterations in renal hemodynamics and function in separate kidneys during stimulation of renal artery nerves in dogs. Am J Physiol. 1951 Nov;167(2):523–530. doi: 10.1152/ajplegacy.1951.167.2.523. [DOI] [PubMed] [Google Scholar]
  5. HUNT C. C. The effect of sympathetic stimulation on mammalian muscle spindles. J Physiol. 1960 May;151:332–341. doi: 10.1113/jphysiol.1960.sp006441. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. IGGO A. Tension receptors in the stomach and the urinary bladder. J Physiol. 1955 Jun 28;128(3):593–607. doi: 10.1113/jphysiol.1955.sp005327. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Kezdi P., Geller E. Baroreceptor control of postganglionic sympathetic nerve discharge. Am J Physiol. 1968 Mar;214(3):427–435. doi: 10.1152/ajplegacy.1968.214.3.427. [DOI] [PubMed] [Google Scholar]
  8. LANDGREN S., NEIL E., ZOTTERMAN Y. The response of the carotid baroceptors to the local administration of drugs. Acta Physiol Scand. 1952;25(1):24–37. doi: 10.1111/j.1748-1716.1952.tb00856.x. [DOI] [PubMed] [Google Scholar]
  9. Nijima A. Afferent discharges from arterial mechanoreceptors in the kidney of the rabbit. J Physiol. 1971 Dec;219(2):477–485. doi: 10.1113/jphysiol.1971.sp009673. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Ninomiya I., Irisawa H. Summation of baroceptor reflex effects on sympathetic nerve activities. Am J Physiol. 1969 Jun;216(6):1330–1336. doi: 10.1152/ajplegacy.1969.216.6.1330. [DOI] [PubMed] [Google Scholar]
  11. STUDY R. S., SHIPLEY R. E. Comparison of direct with indirect renal blood flow, extraction of inulin and diodrast, before and during acute renal nerve stimulation. Am J Physiol. 1950 Nov;163(2):442–453. doi: 10.1152/ajplegacy.1950.163.2.442. [DOI] [PubMed] [Google Scholar]
  12. Sampson S. R., Mills E. Effects of sympathetic stimulation on discharges of carotid sinus baroreceptors. Am J Physiol. 1970 Jun;218(6):1650–1653. doi: 10.1152/ajplegacy.1970.218.6.1650. [DOI] [PubMed] [Google Scholar]
  13. Vander A. J. Effect of catecholamines and the renal nerves on renin secretion in anesthetized dogs. Am J Physiol. 1965 Sep;209(3):659–662. doi: 10.1152/ajplegacy.1965.209.3.659. [DOI] [PubMed] [Google Scholar]

Articles from The Journal of Physiology are provided here courtesy of The Physiological Society

RESOURCES