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. 1975 Jan;15(1):1–10. doi: 10.1016/S0006-3495(75)85787-0

Deformation and fragmentation of human red blood cells in turbulent shear flow.

S P Sutera, M H Mehrjardi
PMCID: PMC1334606  PMID: 1174639

Abstract

By means of glutaraldehyde fixation, human erythrocytes are "frozen" while suspended in turbulent shear flow. As the shearing is increased in steps from 100 to 2,500 dyn/cm2, the deformed cells evolve gradually toward a smooth ellipsoidal shape. At stresses above 2,500 dyn/cm2, approximately, fragmentation of the cells occurs with a concomitant increase in free hemoglobin content of the suspending medium. The photographic evidence suggests that the cells rupture in tension in the bulk flow.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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