Skip to main content
Annals of Surgery logoLink to Annals of Surgery
. 1975 Sep;182(3):334–341. doi: 10.1097/00000658-197509000-00016

Cancer of the breast: Its outcome as measured by the rate of dying and causes of death.

C B Mueller, W Jeffries
PMCID: PMC1343950  PMID: 1174299

Abstract

Mortality forces in women with cancer of the breast were measured by calculating the rate of dying and determining the cause of death in women who develop breast cancer. In the Syracuse-Upstate Medical Center Cancer Registry, 1,513 patients were followed for 15 years. The death curve of this group assumed a major slope characteristic of a single exponential curve, with a half life of 5.9 years. The cause of death was examined in a randomly selected group of patients from the Ontario Cancer Foundation, Hamilton, Ontario, and a group from the Syracuse Registry dying after 10 years. In these 136 patients, 130 died of breast cancer. From the National Cancer Institute Cooperative Studies of 3,225 women undergoing treatment for primary breast cancer, 914 died during the study---705 of cancer of the breast and 209 of competing risks. These data suggest that 80-85% of all women who die after developing cancer of the breast die of their breast cancer. Modification of the time of dying (rate of dying) or cause of death should be used as objectives of management rather than 5-year survival figures.

Full text

PDF
340

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. EDERER F. A simple method for determing standard errors of survival rates, with tables. J Chronic Dis. 1960 Jun;11:632–645. doi: 10.1016/0021-9681(60)90062-x. [DOI] [PubMed] [Google Scholar]
  2. EDERER F., AXTELL L. M., CUTLER S. J. The relative survival rate: a statistical methodology. Natl Cancer Inst Monogr. 1961 Sep;6:101–121. [PubMed] [Google Scholar]
  3. Fisher B., Ravdin R. G., Ausman R. K., Slack N. H., Moore G. E., Noer R. J. Surgical adjuvant chemotherapy in cancer of the breast: results of a decade of cooperative investigation. Ann Surg. 1968 Sep;168(3):337–356. doi: 10.1097/00000658-196809000-00004. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Kraus A. S., Oppenheim A. Trend of mortality from cancer of the breast. JAMA. 1965 Oct 4;194(1):89–90. [PubMed] [Google Scholar]
  5. LILIENFELD A. M. THE EPIDEMIOLOGY OF BREAST CANCER. Cancer Res. 1963 Oct;23:1503–1513. [PubMed] [Google Scholar]
  6. Von Essen C. F., Shedd D. P., Connelly R. R., Eisenberg H. Cancer of the larynx in Connecticut, 1935-1959. Cancer. 1968 Dec;22(6):1315–1322. doi: 10.1002/1097-0142(196811)22:6<1315::aid-cncr2820220631>3.0.co;2-f. [DOI] [PubMed] [Google Scholar]
  7. Zumoff B., Hart H., Hellman L. Considerations of mortality in certain chronic diseases. Ann Intern Med. 1966 Mar;64(3):595–601. doi: 10.7326/0003-4819-64-3-595. [DOI] [PubMed] [Google Scholar]

Articles from Annals of Surgery are provided here courtesy of Lippincott, Williams, and Wilkins

RESOURCES