Skip to main content
Annals of Surgery logoLink to Annals of Surgery
. 1976 Sep;184(3):279–288. doi: 10.1097/00000658-197609000-00005

Risks in therapeutic portacaval and splenorenal shunts.

R A Malt, J Szczerban, R B Malt
PMCID: PMC1344381  PMID: 962396

Abstract

Analyses of the records of 120 patients who underwent portacaval shunting (PCS, 57%) or splenorenal shunting (SRS, 43%) from 1966-1973 disclosed that patients in each group undergoing elective shunts had the same preoperative physical condition and postoperative mortality rates (approximately 20%). Although the post-operative death rate from emergency shunts was 48%, patients having these procedures were poorer risks. Long-term incidences of encephalopathy were the same, irrespective of the type of shunt (PCS, 46%; SRS 36%, P greater than 0.5). Despite comparisons of data most unfavorable for PCS, 5-year survival rates were also the same after either type of shunt (all PCS, 29 +/- 7.5%, SRS, 42.0 +/- 7.4%, P = 0.23). The survival rate after elective PCS was also the same as after SRS during the entire 5-year period. However, the survival after all elective PCS and SRS was significantly greater than after emergency PCS (P range = 0.005-0.038); the poorer results of emergency shunting could be partly attributed to the poorer condition of patients selected. A numerical score based on serum bilirubin concentrations, ascites, and urgency of shunting reliably predicts postoperative mortality. Long-term encephalopathy is predicted by a history of encephalopathy and the urgency of shunting.

Full text

PDF
281

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Barnes B. A., Ackroyd F. W., Battit G. E., Kantrowitz P. A., Schapiro R. H., Strole W. E., Jr, Todd D. P., McDermott W. V., Jr Elective portasystemic shunts: morbidity and survival data. Ann Surg. 1971 Jul;174(1):76–84. doi: 10.1097/00000658-197107010-00013. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Bismuth H., Franco D., Hepp J. Portal-systemic shunt in hepatic cirrhosis: does the type of shunt decisively influence the clinical result? Ann Surg. 1974 Feb;179(2):209–218. doi: 10.1097/00000658-197402000-00019. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Britton R. C., Voorhees A. B., Jr, Price J. B., Jr Selective portal decompression. Surgery. 1970 Jan;67(1):104–113. [PubMed] [Google Scholar]
  4. CUTLER S. J., EDERER F. Maximum utilization of the life table method in analyzing survival. J Chronic Dis. 1958 Dec;8(6):699–712. doi: 10.1016/0021-9681(58)90126-7. [DOI] [PubMed] [Google Scholar]
  5. Campbell D. P., Parker D. E., Anagnostopoulos C. E. Survival prediction in portacaval shunts: a computerized statistical analysis. Am J Surg. 1973 Dec;126(6):748–751. doi: 10.1016/s0002-9610(73)80062-5. [DOI] [PubMed] [Google Scholar]
  6. Drapanas T., LoCicero J., 3rd, Dowling J. B. Hemodynamics of the interposition mesocaval shunt. Ann Surg. 1975 May;181(5):523–533. doi: 10.1097/00000658-197505000-00004. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Felix W. R., Jr, Myerson R. M., Sigel B., Perrin E. B., Jackson F. C. The effect of portacaval shunt on hypersplenism. Surg Gynecol Obstet. 1974 Dec;139(6):899–904. [PubMed] [Google Scholar]
  8. Foster J. H., Ellison L. H., Donovan T. J., Anderson A. Quantity and quality of survival after portosystemic shunts. Am J Surg. 1971 Apr;121(4):490–501. doi: 10.1016/0002-9610(71)90245-5. [DOI] [PubMed] [Google Scholar]
  9. Gliedman M. L. The mesocaval shunt for portal hypertension. Am J Gastroenterol. 1971 Oct;56(4):323–333. [PubMed] [Google Scholar]
  10. Hermann R. E., Rodriguez A. E., McCormack L. J. Selection of patients for portal-systemic shunts. JAMA. 1966 Jun 20;196(12):1039–1044. [PubMed] [Google Scholar]
  11. Inokuchi K., Kobayashi M., Ogawa Y., Saku M., Nagasue N. Results of left gastric vena caval shunt for esophageal varices: Analysis of one hundred clinical cases. Surgery. 1975 Nov;78(5):628–636. [PubMed] [Google Scholar]
  12. Jackson F. C., Perrin E. B., Felix W. R., Smith A. G. A clinical investigation of the portacaval shunt. V. Survival analysis of the therapeutic operation. Ann Surg. 1971 Oct;174(4):672–701. doi: 10.1097/00000658-197110000-00012. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Kardel T., Lund Y., Olsen P. Z., Möllgaard V., Gammeltoft A. Encephalopathy and portacaval anastomosis. Scand J Gastroenterol. 1970;5(8):681–685. [PubMed] [Google Scholar]
  14. Lecompte Y., Metreau J. M., Sancho H. S., Bismuth H. Prediction of mortality in cirrhosis of the liver. Surg Gynecol Obstet. 1974 Oct;139(4):529–530. [PubMed] [Google Scholar]
  15. Maillard J. N., Clot P., Coste T. Preoperative parameters influencing survival in patients with elective portacaval shunts. Digestion. 1974;10(2):129–137. doi: 10.1159/000197532. [DOI] [PubMed] [Google Scholar]
  16. McDermott W. V., Jr, Barnes B. A., Nardi G. L., Ackroyd F. W. Postshunt encephalopathy. Surg Gynecol Obstet. 1968 Mar;126(3):585–590. [PubMed] [Google Scholar]
  17. Mikkelsen W. P. Therapeutic portacaval shunt. Preliminary data on controlled trial and morbid effects of acute hyaline necrosis. Arch Surg. 1974 Mar;108(3):302–305. doi: 10.1001/archsurg.1974.01350270036007. [DOI] [PubMed] [Google Scholar]
  18. Mutchnick M. G., Lerner E., Conn H. O. Portal-systemic encephalopathy and portacaval anastomosis: a prospective, controlled investigation. Gastroenterology. 1974 May;66(5):1005–1019. [PubMed] [Google Scholar]
  19. Nakache J. P., Hecht Y., Georgakopoulos H., Salmon D., Garçon C., Giard M. H. Le pronostic des anastomoses portosystémiques pour cirrhose: apport de l'analyse discriminante et de l'analyse factorielle des correspondances. Acta Gastroenterol Belg. 1971 Feb;34(2):248–262. [PubMed] [Google Scholar]
  20. Orloff M. J., Charters A. C., 3rd, Chandler J. G., Condon J. K., Grambort D. E., Modafferi T. R., Levin S. E., Brown N. B., Sviokla S. C., Knox D. G. Portacaval shunt as emergency procedure in unselected patients with alcoholic cirrhosis. Surg Gynecol Obstet. 1975 Jul;141(1):59–68. [PubMed] [Google Scholar]
  21. Ottinger L. W., Moncure A. C. Transthoracic ligation of bleeding esophageal varices in patients with intraheptic portal obstruction. Ann Surg. 1974 Jan;179(1):35–38. doi: 10.1097/00000658-197401000-00007. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Panke W. F., Rousselot L. M., Burcheli A. R. A sixteen-year experience with end-to-side portacaval shunt for varical hemorrhage: analysis of data and comparison with other types of portasystemic anastomoses. Ann Surg. 1968 Dec;168(6):957–965. doi: 10.1097/00000658-196812000-00003. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Prandi D., Rueff B., Roche-Sicot J., Sicot C., Maillard J. N., Benhamou J. P., Fauvert R. Life-threatening hemorrhage of the digestive tract in cirrhotic patients. An assessment of the postoperative mortality after emergency portacaval shunt. Am J Surg. 1976 Feb;131(2):204–209. doi: 10.1016/0002-9610(76)90098-2. [DOI] [PubMed] [Google Scholar]
  24. Resnick R. H., Iber F. L., Ishihara A. M., Chalmers T. C., Zimmerman H. A controlled study of the therapeutic portacaval shunt. Gastroenterology. 1974 Nov;67(5):843–857. [PubMed] [Google Scholar]
  25. Riddell A. G., Bloor K., Hobbs K. E., Jacquet N. Elective splenorenal anastomosis. Br Med J. 1972 Mar 18;1(5802):731–732. doi: 10.1136/bmj.1.5802.731. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. Stipa S., Thau A., Cavallaro A., Rossi P. A technique for mesentericocaval shunt. Surg Gynecol Obstet. 1973 Aug;137(2):285–287. [PubMed] [Google Scholar]
  27. Turcotte J. G., Wallin V. W., Jr, Child C. G., 3rd End to side versus side to side portacaval shunts in patients with hepatic cirrhosis. Am J Surg. 1969 Jan;117(1):108–116. doi: 10.1016/0002-9610(69)90291-8. [DOI] [PubMed] [Google Scholar]
  28. Voorhees A. B., Jr, Price J. B., Jr, Britton R. C. Portasystemic shunting procedures for portal hypertension. Twenty-six year experience in adults with cirrhosis of the liver. Am J Surg. 1970 May;119(5):501–505. doi: 10.1016/0002-9610(70)90162-5. [DOI] [PubMed] [Google Scholar]
  29. Warren W. D., Rudman D., Millikan W., Galambos J. T., Salam A. A., Smith R. B., 3rd The metabolic basis of portasystemic encephalopathy and the effect of selective vs nonselective shunts. Ann Surg. 1974 Oct;180(4):573–579. doi: 10.1097/00000658-197410000-00022. [DOI] [PMC free article] [PubMed] [Google Scholar]
  30. Windle R., Peacock J. H. Prognosis after portocaval anastomosis: a 15-year follow-up. Br J Surg. 1975 Sep;62(9):701–706. doi: 10.1002/bjs.1800620908. [DOI] [PubMed] [Google Scholar]
  31. Wirthlin L. S., Linton R. R., Ellis D. S. Transthoracoesophageal ligation of bleeding esophageal varices: a reappraisal. Arch Surg. 1974 Nov;109(5):688–692. doi: 10.1001/archsurg.1974.01360050082018. [DOI] [PubMed] [Google Scholar]
  32. Wirthlin L. S., Van Urk H., Malt R. B., Malt R. A. Predictors of surgical mortality in patients with cirrhosis and nonvariceal gastroduodenal bleeding. Surg Gynecol Obstet. 1974 Jul;139(1):65–68. [PubMed] [Google Scholar]

Articles from Annals of Surgery are provided here courtesy of Lippincott, Williams, and Wilkins

RESOURCES