Abstract
From 1966 through 1970 we performed resections in 216 patients with carcinoma of the large bowel. The relative five year survival for all patients was 65.5%. The relative five year survival for all potentially curable patients was 80.4%. Patients with positive lymph nodes and full-thickness penetration of their tumors had a five year survival of 70.5% and a 10 year survival of 60.5%. In performing this study we have tested the principles of wide anatomical resection and radical lymphadenectomy. For their specific influences on survival we have also examined stage, site, age, sex, race, margins, local recurrence, hypogastric lymph node dissection, serosal penetration and various aspects of nodal status. The information derived from these parameters has confirmed our hypothesis that survival is directly related to radical anatomical resection and lymphadenectomy. For rectal cancer, extensive resection also reduces the incidence of local recurrence. We are persuaded that the principles of operation for large-bowel cancer are valid and that they merit universal adoption.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- ASTLER V. B., COLLER F. A. The prognostic significance of direct extension of carcinoma of the colon and rectum. Ann Surg. 1954 Jun;139(6):846–852. doi: 10.1097/00000658-195406000-00015. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Block G. E., Enker W. E. Survival after operations for rectal carcinoma in patients over 70 years of age. Ann Surg. 1971 Sep;174(3):521–529. doi: 10.1097/00000658-197109000-00018. [DOI] [PMC free article] [PubMed] [Google Scholar]
- COLE W. H., PACKARD D., SOUTHWICK H. W. Carcinoma of the colon with special reference to prevention of recurrence. J Am Med Assoc. 1954 Aug 28;155(18):1549–1553. doi: 10.1001/jama.1954.03690360001001. [DOI] [PubMed] [Google Scholar]
- DEDDISH M. R., STEARNS M. W., Jr Anterior resection for carcinoma of the rectum and rectosigmoid area. Ann Surg. 1961 Dec;154:961–966. [PMC free article] [PubMed] [Google Scholar]
- Jamieson J. K., Dobson J. F. VII. Lymphatics of the Colon: With Special Reference to the Operative Treatment of Cancer of the Colon. Ann Surg. 1909 Dec;50(6):1077–1090. doi: 10.1097/00000658-190912000-00007. [DOI] [PMC free article] [PubMed] [Google Scholar]
- ROSI P. A., CAHILL W. J., CAREY J. A ten year study of hemicolectomy in the treatment of carcinoma of the left half of the colon. Surg Gynecol Obstet. 1962 Jan;114:15–24. [PubMed] [Google Scholar]
- STEARNS M. W., Jr, DEDDISH M. R. Five-year results of abdominopelvic lymph node dissection for carcinoma of the rectum. Dis Colon Rectum. 1959 Mar-Apr;2(2):169–172. doi: 10.1007/BF02616711. [DOI] [PubMed] [Google Scholar]
- Stearns M. W., Jr Benign and malignant neoplasms of colon and rectum. Diagnosis and management. Surg Clin North Am. 1978 Jun;58(3):605–618. doi: 10.1016/s0039-6109(16)41542-2. [DOI] [PubMed] [Google Scholar]
- Turnbull R. B., Jr, Kyle K., Watson F. R., Spratt J. Cancer of the colon: the influence of the no-touch isolation technic on survival rates. Ann Surg. 1967 Sep;166(3):420–427. doi: 10.1097/00000658-196709000-00010. [DOI] [PMC free article] [PubMed] [Google Scholar]