Skip to main content
PMC home page
Annals of Surgery logoLink to Annals of Surgery
. 1980 May;191(5):593–598. doi: 10.1097/00000658-198005000-00011

Primary lymphoma of the gastrointestinal tract.

K Contreary, F C Nance, W F Becker
PMCID: PMC1344744  PMID: 6989331

Abstract

Primary gastrointestinal lymphoma represents approximately 1% of all gastrointestinal neoplasms. Gastric involvement is more common than small or large intestine and carries a better prognosis. Abdominal pain and weight loss may be the only manifestations and may be present for months or years before the diagnosis is made. Perforation and obstruction occur infrequently. Multiple tumors constitute 8% of cases. Although barium studies and endoscopy reveal the lesion in a high percentage of cases, exploratory celiotomy is not infrequently required for diagnosis. Only one-third of lymphomas are confined to the bowel at laparotomy. Histologically one-third are reticulum cell sarcomas and the remainder lymphosarcoma or lymphocytic lymphoma. Five year survival overall was 38%. Curative resections yielded a survival of 60% regardless of site while palliative resections offered only a 17% chance of cure. As expected, survival was inversely proportional to extent of nodal spread. Postoperative radiotherapy is recommended for residual disease.

Full text

PDF
597

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ALLEN A. W., DONALDSON G., SNIFFEN R. C., GOODALE F., Jr Primary malignant lymphoma of the gastro-intestinal tract. Ann Surg. 1954 Sep;140(3):428–438. doi: 10.1097/00000658-195409000-00017. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. AZZOPARDI J. G., MENZIES T. Primary malignant lymphoma of the alimentary tract. Br J Surg. 1960 Jan;47:358–366. doi: 10.1002/bjs.18004720404. [DOI] [PubMed] [Google Scholar]
  3. Berg J. W. Primary lymphomas of the human gastrointestinal tract. Natl Cancer Inst Monogr. 1969 Aug;32:211–220. [PubMed] [Google Scholar]
  4. Burgess J. N., Dockerty M. B., ReMine W. H. Sarcomatous lesions of the stomach. Ann Surg. 1971 May;173(5):758–766. doi: 10.1097/00000658-197105000-00015. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. FRAZER J. W., Jr Malignant lymphomas of the gastrointestinal tract. Surg Gynecol Obstet. 1959 Feb;108(2):182–190. [PubMed] [Google Scholar]
  6. Glick D. D., Soule E. H. Primary malignant lymphoma of colon or appendix. Report of 27 cases. Arch Surg. 1966 Jan;92(1):144–151. doi: 10.1001/archsurg.1966.01320190146033. [DOI] [PubMed] [Google Scholar]
  7. Hertzer N. R., Hoerr S. O. An interpretive review of lymphoma of the stomach. Surg Gynecol Obstet. 1976 Jul;143(1):113–124. [PubMed] [Google Scholar]
  8. Lim F. E., Hartman A. S., Tan E. G., Cady B., Meissner W. A. Factors in the prognosis of gastric lymphoma. Cancer. 1977 Apr;39(4):1715–1720. doi: 10.1002/1097-0142(197704)39:4<1715::aid-cncr2820390449>3.0.co;2-m. [DOI] [PubMed] [Google Scholar]
  9. Loehr W. J., Mujahed Z., Zahn F. D., Gray G. F., Thorbjarnarson B. Primary lymphoma of the gastrointestinal tract: a review of 100 cases. Ann Surg. 1969 Aug;170(2):232–238. doi: 10.1097/00000658-196908000-00011. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Moore T. N., Scruggs H. J., Marks R. D., Jr, Wallace K. M. Malignant lymphoma of the stomach. J S C Med Assoc. 1977 Jul;73(7):305-8, 313. [PubMed] [Google Scholar]
  11. Naqvi M. S., Burrows L., Kark A. E. Lymphoma of the gastrointestinal tract: prognostic guides based on 162 cases. Ann Surg. 1969 Aug;170(2):221–231. doi: 10.1097/00000658-196908000-00010. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Novak S., Caraveo J., Trowbridge A. A., Peterson R. F., White R. R., 3rd Primary lymphomas of the gastrointestinal tract. South Med J. 1979 Sep;72(9):1154–1158. doi: 10.1097/00007611-197909000-00023. [DOI] [PubMed] [Google Scholar]
  13. WARREN K. W., LITTLEFIELD J. B. Malignant lymphomas of the gastrointestinal tract. Surg Clin North Am. 1955 Jun;LAHEY:735–746. doi: 10.1016/s0039-6109(16)34590-x. [DOI] [PubMed] [Google Scholar]
  14. WARREN K. W. Malignant lymphoma of the duodenum, small intestine and colon. Surg Clin North Am. 1959 Jun;39(3):725–735. doi: 10.1016/s0039-6109(16)35798-x. [DOI] [PubMed] [Google Scholar]
  15. WEAVER D. K., BATSAKIS J. G. PRIMARY LYMPHOMAS OF THE SMALL INTESTINE. Am J Gastroenterol. 1964 Dec;42:620–625. [PubMed] [Google Scholar]
  16. Warren S., Lulenski C. R. PRIMARY, SOLITARY LYMPHOID TUMORS OF THE GASTRO-INTESTINAL TRACT. Ann Surg. 1942 Jan;115(1):1–12. doi: 10.1097/00000658-194201000-00002. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Wychulis A. R., Beahrs O. H., Woolner L. B. Malignant lymphoma of the colon. A study of 69 cases. Arch Surg. 1966 Aug;93(2):215–225. doi: 10.1001/archsurg.1966.01330020007002. [DOI] [PubMed] [Google Scholar]

Articles from Annals of Surgery are provided here courtesy of Lippincott, Williams, and Wilkins

RESOURCES