Skip to main content
American Journal of Public Health logoLink to American Journal of Public Health
. 1988 Mar;78(3):273–275. doi: 10.2105/ajph.78.3.273

Do regional variations in prevalence of cryptosporidiosis occur? The central Ohio experience.

A C Hamoudi 1, S J Qualman 1, M J Marcon 1, M Hribar 1, H J McClung 1, R D Murray 1, H J Cannon 1
PMCID: PMC1349175  PMID: 3341496

Abstract

We screened 2,780 consecutive stool specimens submitted for routine ova and parasite examination to assess the prevalence of cryptosporidiosis in a pediatric patient population in central Ohio. The stools were prepared by formalin-ethyl acetate concentration followed by cold Kinyoun acid-fast stain of the sediment. In addition, 912 consecutive intestinal biopsies were monitored for the presence of the parasite. Cryptosporidium oocysts were found in only 0.3 per cent of stool specimens (seven specimens from three patients) and in none of the intestinal biopsies. Due to this low prevalence of cryptosporidiosis, we conclude that routine screening of stool specimens for Cryptosporidium sp. is unnecessary in our patient population. Screening should be targeted to immune compromised patients and patients with persistent diarrhea and no apparent etiology. Our study also supports the concept that there are geographic variations in the prevalence of cryptosporidiosis.

Full text

PDF
274

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Alpert G., Bell L. M., Kirkpatrick C. E., Budnick L. D., Campos J. M., Friedman H. M., Plotkin S. A. Outbreak of cryptosporidiosis in a day-care center. Pediatrics. 1986 Feb;77(2):152–157. [PubMed] [Google Scholar]
  2. Baxby D., Hart C. A. The incidence of cryptosporidiosis: a two-year prospective survey in a children's hospital. J Hyg (Lond) 1986 Feb;96(1):107–111. doi: 10.1017/s0022172400062598. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Casemore D. P., Jackson B. Sporadic cryptosporidiosis in children. Lancet. 1983 Sep 17;2(8351):679–679. doi: 10.1016/s0140-6736(83)92552-7. [DOI] [PubMed] [Google Scholar]
  4. Centers for Disease Control (CDC) Cryptosporidiosis among children attending day-care centers--Georgia, Pennsylvania, Michigan, California, New Mexico. MMWR Morb Mortal Wkly Rep. 1984 Oct 26;33(42):599–601. [PubMed] [Google Scholar]
  5. D'Antonio R. G., Winn R. E., Taylor J. P., Gustafson T. L., Current W. L., Rhodes M. M., Gary G. W., Jr, Zajac R. A. A waterborne outbreak of cryptosporidiosis in normal hosts. Ann Intern Med. 1985 Dec;103(6 ):886–888. doi: 10.7326/0003-4819-103-6-886. [DOI] [PubMed] [Google Scholar]
  6. Estevez E. G., Levine J. A. Examination of preserved stool specimens for parasites: lack of value of the direct wet mount. J Clin Microbiol. 1985 Oct;22(4):666–667. doi: 10.1128/jcm.22.4.666-667.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Fayer R., Ungar B. L. Cryptosporidium spp. and cryptosporidiosis. Microbiol Rev. 1986 Dec;50(4):458–483. doi: 10.1128/mr.50.4.458-483.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Garcia L. S., Bruckner D. A., Brewer T. C., Shimizu R. Y. Techniques for the recovery and identification of Cryptosporidium oocysts from stool specimens. J Clin Microbiol. 1983 Jul;18(1):185–190. doi: 10.1128/jcm.18.1.185-190.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Holley H. P., Jr, Dover C. Cryptosporidium: a common cause of parasitic diarrhea in otherwise healthy individuals. J Infect Dis. 1986 Feb;153(2):365–368. doi: 10.1093/infdis/153.2.365. [DOI] [PubMed] [Google Scholar]
  10. Hunt D. A., Shannon R., Palmer S. R., Jephcott A. E. Cryptosporidiosis in an urban community. Br Med J (Clin Res Ed) 1984 Sep 29;289(6448):814–816. doi: 10.1136/bmj.289.6448.814. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Højlyng N., Mølbak K., Jepsen S., Hansson A. P. Cryptosporidiosis in Liberian children. Lancet. 1984 Mar 31;1(8379):734–734. doi: 10.1016/s0140-6736(84)92244-x. [DOI] [PubMed] [Google Scholar]
  12. Højlyng N., Mølbak K., Jepsen S., Hansson A. P. Cryptosporidiosis in Liberian children. Lancet. 1984 Mar 31;1(8379):734–734. doi: 10.1016/s0140-6736(84)92244-x. [DOI] [PubMed] [Google Scholar]
  13. Janoff E. N., Reller L. B. Cryptosporidium species, a protean protozoan. J Clin Microbiol. 1987 Jun;25(6):967–975. doi: 10.1128/jcm.25.6.967-975.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Koch K. L., Phillips D. J., Aber R. C., Current W. L. Cryptosporidiosis in hospital personnel. Evidence for person-to-person transmission. Ann Intern Med. 1985 May;102(5):593–596. doi: 10.7326/0003-4819-102-5-593. [DOI] [PubMed] [Google Scholar]
  15. Marshall A. R., Al-Jumaili I. J., Fenwick G. A., Bint A. J., Record C. O. Cryptosporidiosis in patients at a large teaching hospital. J Clin Microbiol. 1987 Jan;25(1):172–173. doi: 10.1128/jcm.25.1.172-173.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Mata L., Bolaños H., Pizarro D., Vives M. Cryptosporidiosis in children from some highland Costa Rican rural and urban areas. Am J Trop Med Hyg. 1984 Jan;33(1):24–29. doi: 10.4269/ajtmh.1984.33.24. [DOI] [PubMed] [Google Scholar]
  17. Mathan M. M., Venkatesan S., George R., Mathew M., Mathan V. I. Cryptosporidium and diarrhoea in southern Indian children. Lancet. 1985 Nov 23;2(8465):1172–1175. doi: 10.1016/s0140-6736(85)92691-1. [DOI] [PubMed] [Google Scholar]
  18. McNabb S. J., Hensel D. M., Welch D. F., Heijbel H., McKee G. L., Istre G. R. Comparison of sedimentation and flotation techniques for identification of Cryptosporidium sp. oocysts in a large outbreak of human diarrhea. J Clin Microbiol. 1985 Oct;22(4):587–589. doi: 10.1128/jcm.22.4.587-589.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Montessori G. A., Bischoff L. Cryptosporidiosis: a cause of summer diarrhea in children. Can Med Assoc J. 1985 Jun 1;132(11):1285–1285. [PMC free article] [PubMed] [Google Scholar]
  20. Ongerth J. E., Stibbs H. H. Identification of Cryptosporidium oocysts in river water. Appl Environ Microbiol. 1987 Apr;53(4):672–676. doi: 10.1128/aem.53.4.672-676.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Perez-Schael I., Boher Y., Mata L., Perez M., Tapia F. J. Cryptosporidiosis in Venezuelan children with acute diarrhea. Am J Trop Med Hyg. 1985 Jul;34(4):721–722. doi: 10.4269/ajtmh.1985.34.721. [DOI] [PubMed] [Google Scholar]
  22. Ratnam S., Paddock J., McDonald E., Whitty D., Jong M., Cooper R. Occurrence of Cryptosporidium oocysts in fecal samples submitted for routine microbiological examination. J Clin Microbiol. 1985 Sep;22(3):402–404. doi: 10.1128/jcm.22.3.402-404.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Shahid N. S., Rahman A. S., Anderson B. C., Mata L. J., Sanyal S. C. Cryptosporidiosis in Bangladesh. Br Med J (Clin Res Ed) 1985 Jan 12;290(6462):114–115. doi: 10.1136/bmj.290.6462.114. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Skeels M. R., Sokolow R., Hubbard C. V., Foster L. R. Screening for coinfection with Cryptosporidium and Giardia in Oregon public health clinic patients. Am J Public Health. 1986 Mar;76(3):270–273. doi: 10.2105/ajph.76.3.270. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. Soave R., Danner R. L., Honig C. L., Ma P., Hart C. C., Nash T., Roberts R. B. Cryptosporidiosis in homosexual men. Ann Intern Med. 1984 Apr;100(4):504–511. doi: 10.7326/0003-4819-100-4-504. [DOI] [PubMed] [Google Scholar]
  26. Taylor J. P., Perdue J. N., Dingley D., Gustafson T. L., Patterson M., Reed L. A. Cryptosporidiosis outbreak in a day-care center. Am J Dis Child. 1985 Oct;139(10):1023–1025. doi: 10.1001/archpedi.1985.02140120069029. [DOI] [PubMed] [Google Scholar]
  27. Tzipori S., Smith M., Birch C., Barnes G., Bishop R. Cryptosporidiosis in hospital patients with gastroenteritis. Am J Trop Med Hyg. 1983 Sep;32(5):931–934. doi: 10.4269/ajtmh.1983.32.931. [DOI] [PubMed] [Google Scholar]
  28. Wiedermann B. L., Kaplan S. L., Marino B. Prevalence and significance of cryptosporidiosis in children. Pediatr Infect Dis. 1985 May-Jun;4(3):292–293. doi: 10.1097/00006454-198505000-00018. [DOI] [PubMed] [Google Scholar]
  29. Wolfson J. S., Richter J. M., Waldron M. A., Weber D. J., McCarthy D. M., Hopkins C. C. Cryptosporidiosis in immunocompetent patients. N Engl J Med. 1985 May 16;312(20):1278–1282. doi: 10.1056/NEJM198505163122002. [DOI] [PubMed] [Google Scholar]

Articles from American Journal of Public Health are provided here courtesy of American Public Health Association

RESOURCES