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. 1982 Feb;195(2):196–202. doi: 10.1097/00000658-198202000-00013

Management of primary gastric lymphoma.

M H Shiu, M Karas, L Nisce, B J Lee, D A Filippa, P H Lieberman
PMCID: PMC1352442  PMID: 7034661

Abstract

A retrospective study of 51 patients treated for primary gastric lymphoma was made to evaluate the influence of clinicopathologic features and the method of treatment on survival. The lymphocytic type of tumor showed a higher survival rate than the histiocytic type. Tumors that involved only the gastric wall resulted in a five-year survival rate of 62%, as compared with 50% for tumors that involved also the adjacent gastric lymph nodes, and 25% for those involving the distant gastric lymph nodes. Treatment by subtotal, total, or extended forms of gastric resection without postoperative radiation gave a five-year survival rate of 33%. Resection followed by radiation yielded a higher survival rate of 67%. The best results were obtained in 13 patients who received higher doses of radiation: 11 (85%) survived five or more years. One-third of the patients developed manifestations of systemic malignant lymphoma after curative therapy. These observations suggest a planned multimodal therapeutic program for this disease.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BURNETT H. W., HERBERT E. A. The role of irradiation in the treatment of primary malignant lymphoma of the stomach. Radiology. 1956 Nov;67(5):723–728. doi: 10.1148/67.5.723. [DOI] [PubMed] [Google Scholar]
  2. Buchholtz T. W., Welch C. E., Malt R. A. Clinical correlates of resectability and survival in gastric carcinoma. Ann Surg. 1978 Dec;188(6):711–715. doi: 10.1097/00000658-197812000-00001. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Bush R. S., Ash C. L. Primary lymphoma of the gastrointestinal tract. Radiology. 1969 May;92(6):1349–1354. doi: 10.1148/92.6.1349. [DOI] [PubMed] [Google Scholar]
  4. Bush R. S., Gospodarowicz M., Sturgeon J., Alison R. Radiation therapy of localized non-Hodgkin's lymphoma. Cancer Treat Rep. 1977 Sep;61(6):1129–1136. [PubMed] [Google Scholar]
  5. CRILE G., Jr, HAZARD J. B., ALLEN K. L. Primary lymphosarcoma of the stomach. Ann Surg. 1952 Jan;135(1):39–43. doi: 10.1097/00000658-195201000-00005. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Carbone P. P., Kaplan H. S., Musshoff K., Smithers D. W., Tubiana M. Report of the Committee on Hodgkin's Disease Staging Classification. Cancer Res. 1971 Nov;31(11):1860–1861. [PubMed] [Google Scholar]
  7. Connors J., Wise L. Management of gastric lymphomas. Am J Surg. 1974 Jan;127(1):102–108. doi: 10.1016/0002-9610(74)90018-x. [DOI] [PubMed] [Google Scholar]
  8. Dupont J. B., Jr, Lee J. R., Burton G. R., Cohn I., Jr Adenocarcinoma of the stomach: review of 1,497 cases. Cancer. 1978 Mar;41(3):941–947. doi: 10.1002/1097-0142(197803)41:3<941::aid-cncr2820410323>3.0.co;2-m. [DOI] [PubMed] [Google Scholar]
  9. Filippa D. A., Lieberman P. H., Erlandson R. A., Koziner B., Siegal F. P., Turnbull A., Zimring A., Good R. A. A study of malignant lymphomas using light and ultramicroscopic, cytochemical and immunologic technics: correlation with clinical features. Am J Med. 1978 Feb;64(2):259–268. doi: 10.1016/0002-9343(78)90054-2. [DOI] [PubMed] [Google Scholar]
  10. Freeman C., Berg J. W., Cutler S. J. Occurrence and prognosis of extranodal lymphomas. Cancer. 1972 Jan;29(1):252–260. doi: 10.1002/1097-0142(197201)29:1<252::aid-cncr2820290138>3.0.co;2-#. [DOI] [PubMed] [Google Scholar]
  11. HICKS E. B., RAPPAPORT H., WINTER W. J. Follicular lymphoma; a re-evaluation of its position in the scheme of malignant lymphoma, based on a survey of 253 cases. Cancer. 1956 Jul-Aug;9(4):792–821. doi: 10.1002/1097-0142(195607/08)9:4<792::aid-cncr2820090429>3.0.co;2-b. [DOI] [PubMed] [Google Scholar]
  12. Hertzer N. R., Hoerr S. O. An interpretive review of lymphoma of the stomach. Surg Gynecol Obstet. 1976 Jul;143(1):113–124. [PubMed] [Google Scholar]
  13. Hoerr S. O., McCormack L. J., Hertzer N. R. Prognosis in gastric lymphoma. Arch Surg. 1973 Aug;107(2):155–158. doi: 10.1001/archsurg.1973.01350200029008. [DOI] [PubMed] [Google Scholar]
  14. JACOBS D. S. PRIMARY GASTRIC MALIGNANT LYMPHOMA AND PSEUDOLYMPHOMA. Am J Clin Pathol. 1963 Oct;40:379–394. doi: 10.1093/ajcp/40.4.379. [DOI] [PubMed] [Google Scholar]
  15. Joseph J. I., Lattes R. Gastric lymphosarcoma. Clinicopathologic analysis of 71 cases and its relation to disseminated lymphosarcoma. Am J Clin Pathol. 1966 Jun;45(6):653–669. doi: 10.1093/ajcp/45.6.653. [DOI] [PubMed] [Google Scholar]
  16. Lim F. E., Hartman A. S., Tan E. G., Cady B., Meissner W. A. Factors in the prognosis of gastric lymphoma. Cancer. 1977 Apr;39(4):1715–1720. doi: 10.1002/1097-0142(197704)39:4<1715::aid-cncr2820390449>3.0.co;2-m. [DOI] [PubMed] [Google Scholar]
  17. MARSHALL S. F., MEISSNER W. A. Sarcoma of the stomach. Ann Surg. 1950 Jun;131(6):824–837. doi: 10.1097/00000658-195006000-00003. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Rosenberg S. A. Current concepts in cancer: non-Hodgkin's lymphoma--selection of treatment on the basis of histologic type. N Engl J Med. 1979 Oct 25;301(17):924–928. doi: 10.1056/NEJM197910253011706. [DOI] [PubMed] [Google Scholar]
  19. Shiu M. H., Papacristou D. N., Kosloff C., Eliopoulos G. Selection of operative procedure for adenocarcinoma of the midstomach. Twenty years' experience with implications for future treatment strategy. Ann Surg. 1980 Dec;192(6):730–737. doi: 10.1097/00000658-198012000-00007. [DOI] [PMC free article] [PubMed] [Google Scholar]

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