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. 1973 Feb;177(2):159–163. doi: 10.1097/00000658-197302000-00005

On the in vivo clearance and detoxification of endotoxin by lung and liver.

K Mori, K Matsumoto, H Gans
PMCID: PMC1355554  PMID: 4572780

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BENACERRAF B., SEBESTYEN M. M. Effect of bacterial endotoxins on the reticuloendothelial system. Fed Proc. 1957 Sep;16(3):860–867. [PubMed] [Google Scholar]
  2. BIOZZI G., BENACERRAF B., HALPERN B. N. The effect of Salm. typhi and its endotoxin on the phagocytic activity of the reticuloendothelial system in mice. Br J Exp Pathol. 1955 Jun;36(3):226–235. [PMC free article] [PubMed] [Google Scholar]
  3. BRAUDE A. I., CAREY F. J., SUTHERLAND D., ZALESKY M. Studies with radioactive endotoxin. I. The use of Cr51 to label endotoxin of Escherichia coli. J Clin Invest. 1955 Jun;34(6):850–857. doi: 10.1172/JCI103140. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. BRAUDE A. I., CAREY F. J., ZALESKY M. Studies with radioactive endotoxin. II. Correlation of physiologic effects with distribution of radioactivity in rabbits injected with radioactive sodium chromate. J Clin Invest. 1955 Jun;34(6):858–866. doi: 10.1172/JCI103141. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Bjorneboe M., Prytz H., Orskov F. Antibodies to intestinal microbes in serum of patients with cirrhosis of the liver. Lancet. 1972 Jan 8;1(7741):58–60. doi: 10.1016/s0140-6736(72)90060-8. [DOI] [PubMed] [Google Scholar]
  6. CORWIN L. M., FARRAR W. E., Jr NATURE OF THE ENDOTOXIN-INACTIVATING PRINCIPLE IN GUINEA-PIG LIVER. J Bacteriol. 1964 Apr;87:832–837. doi: 10.1128/jb.87.4.832-837.1964. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Filkins J. P. Bioassay of endotoxin inactivation in the lead-sensitized rat. Proc Soc Exp Biol Med. 1970 Jul;134(3):610–612. doi: 10.3181/00379727-134-34844. [DOI] [PubMed] [Google Scholar]
  8. Filkins J. P. Hepatic lysosomes and the inactivation of endotoxin. J Reticuloendothel Soc. 1971 May;9(5):480–490. [PubMed] [Google Scholar]
  9. Gans H., Mori K., Lindsey E., Kaster B., Richter D., Quinlan R., Dineen P. A., Tan B. H. Septicemia as a manifestation of acute liver failure. Surg Gynecol Obstet. 1971 May;132(5):783–790. [PubMed] [Google Scholar]
  10. Gans H., Stern R., Tan B. H. On the in vivo clearance of thrombin. Thromb Diath Haemorrh. 1969 Aug 31;22(1):1–12. [PubMed] [Google Scholar]
  11. Kocsár L. T., Bertók L., Várterész V. Effect of bile acids on the intestinal absorption of endotoxin in rats. J Bacteriol. 1969 Oct;100(1):220–223. doi: 10.1128/jb.100.1.220-223.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Levin J., Tomasulo P. A., Oser R. S. Detection of endotoxin in human blood and demonstration of an inhibitor. J Lab Clin Med. 1970 Jun;75(6):903–911. [PubMed] [Google Scholar]
  13. Oroszlan S., McFarland V. W., Mora P. T., Shear M. J. Reversible inactivation of an endotoxin by plasma proteins. Ann N Y Acad Sci. 1966 Jun 30;133(2):622–628. doi: 10.1111/j.1749-6632.1966.tb52393.x. [DOI] [PubMed] [Google Scholar]
  14. RAVIN H. A., ROWLEY D., JENKINS C., FINE J. On the absorption of bacterial endotoxin from the gastro-intestinal tract of the normal and shocked animal. J Exp Med. 1960 Nov 1;112:783–792. doi: 10.1084/jem.112.5.783. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. RUTENBURG S. H., SCHWEINBURG F. B., FINE J. In vitro detoxification of bacterial endotoxin by macrophages. J Exp Med. 1960 Nov 1;112:801–807. doi: 10.1084/jem.112.5.801. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Ratnoff O. D. Some relationships among hemostasis, fibrinolytic phenomena, immunity, and the inflammatory response. Adv Immunol. 1969;10:145–227. doi: 10.1016/s0065-2776(08)60417-4. [DOI] [PubMed] [Google Scholar]
  17. Rudbach J. A., Anacker R. L., Haskins W. T., Johnson A. G., Milner K. C., Ribi E. Physical aspects of reversible inactivation of endotoxin. Ann N Y Acad Sci. 1966 Jun 30;133(2):629–643. doi: 10.1111/j.1749-6632.1966.tb52394.x. [DOI] [PubMed] [Google Scholar]
  18. Rudbach J. A., Johnson A. G. Alteration and restoration of endotoxin activity after complexing with plasma proteins. J Bacteriol. 1966 Oct;92(4):892–898. doi: 10.1128/jb.92.4.892-898.1966. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. SANFORD J. P., NOYES H. E. Studies on the absorption of Escherichia coli endotoxin from the gastrointestinal tract of dogs in the pathogenesis of irreversible hemorrhagic shock. J Clin Invest. 1958 Oct;37(10):1425–1435. doi: 10.1172/JCI103733. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Schultz D. R., Becker E. L. The alteration of endotoxin by postheparin plasma and its purified fractions. I. Comparison of the ability of guinea pig postheparin and normal plasma to detoxify endotoxin. J Immunol. 1967 Mar;98(3):473–481. [PubMed] [Google Scholar]
  21. Schultz D. R., Becker E. L. The alteration of endotoxin by postheparin plasma and purified fractions. II. Relationship of the endotoxin detoxifying activity of euglobulin from postheparin plasma to lipoprotein lipase. J Immunol. 1967 Mar;98(3):482–489. [PubMed] [Google Scholar]
  22. Selye H., Tuchweber B., Bertók L. Effect of lead acetate on the susceptibility of rats to bacterial endotoxins. J Bacteriol. 1966 Feb;91(2):884–890. doi: 10.1128/jb.91.2.884-890.1966. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. TRAPANI R. J., WARAVDEKAR V. S., LANDY M., SHEAR M. J. In vitro inactivation of endotoxin by an intracellular agent from rabbit liver. J Infect Dis. 1962 Mar-Apr;110:135–142. doi: 10.1093/infdis/110.2.135. [DOI] [PubMed] [Google Scholar]
  24. Triger D. R., Alp M. H., Wright R. Bacterial and dietary antibodies in liver disease. Lancet. 1972 Jan 8;1(7741):60–63. doi: 10.1016/s0140-6736(72)90061-x. [DOI] [PubMed] [Google Scholar]

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