Skip to main content
PMC home page
The Journal of Physiology logoLink to The Journal of Physiology
. 1960 Oct;153(3):423–432. doi: 10.1113/jphysiol.1960.sp006544

The state of Factor I in rat brain: the effects of metabolic conditions and drugs

K A C Elliott, N M van Gelder
PMCID: PMC1359760  PMID: 13726452

Full text

PDF
425

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BAXTER C. F., ROBERTS E. Elevation of gamma-aminobutyric acid in rat brain with hydroxylamine. Proc Soc Exp Biol Med. 1959 Aug-Sep;101:811–815. doi: 10.3181/00379727-101-25105. [DOI] [PubMed] [Google Scholar]
  2. DAWSON R. M. C. Studies on the glutamine and glutamic acid content of the rat brain during insulin hypoglycaemia. Biochem J. 1950 Oct;47(4):386–391. doi: 10.1042/bj0470386. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. DAWSON R. M. Cerebral amino acids in fluoroacetate-poisoned, anaesthetised and hypoglycaemic rats. Biochim Biophys Acta. 1953 Aug;11(4):548–552. doi: 10.1016/0006-3002(53)90094-8. [DOI] [PubMed] [Google Scholar]
  4. EADE N. R. The storage and release of catechol amines. Rev Can Biol. 1958 Sep;17(3):299–311. [PubMed] [Google Scholar]
  5. EIDELBERG E., BAXTER C. F., ROBERTS E., SALDIAS C. A., FRENCH J. D. Anticonvulsant properties of hydroxylamine and elevation of cerebral gamma-aminobutyric acid in cats. Proc Soc Exp Biol Med. 1959 Aug-Sep;10:815–817. doi: 10.3181/00379727-101-25106. [DOI] [PubMed] [Google Scholar]
  6. ELLIOTT K. A., FLOREY E. Factor I--inhibitory factor from brain; assay; conditions in brain; simulating and antagonizing substances. J Neurochem. 1956 Dec;1(2):181–192. doi: 10.1111/j.1471-4159.1956.tb12071.x. [DOI] [PubMed] [Google Scholar]
  7. ELLIOTT K. A., JASPER H. H. Gammaaminobutyric acid. Physiol Rev. 1959 Apr;39(2):383–406. doi: 10.1152/physrev.1959.39.2.383. [DOI] [PubMed] [Google Scholar]
  8. ELLIOTT K. A., VAN GELDER N. M. Occlusion and metabolism of gamma-aminobutyric acid by brain tissue. J Neurochem. 1958 Oct;3(1):28–40. doi: 10.1111/j.1471-4159.1958.tb12606.x. [DOI] [PubMed] [Google Scholar]
  9. ELLIOTT K. A. gamma-Aminobutyric acid and factor I. Rev Can Biol. 1958 Sep;17(3):367–388. [PubMed] [Google Scholar]
  10. FLOREY E. An inhibitory and an excitatory factor of mammalian central nervous system, and their action of a single sensory neuron. Arch Int Physiol. 1954 Feb;62(1):33–53. doi: 10.3109/13813455409145367. [DOI] [PubMed] [Google Scholar]
  11. FLOREY E., MCLENNAN H. The release of an inhibitory substance from mammalian brain, and its effect on peripheral synaptic transmission. J Physiol. 1955 Aug 29;129(2):384–392. doi: 10.1113/jphysiol.1955.sp005361. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. HEBB C. O., WHITTAKER V. P. Intracellular distributions of acetylcholine and choline acetylase. J Physiol. 1958 Jun 18;142(1):187–196. doi: 10.1113/jphysiol.1958.sp006008. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. IWAMA K., JASPER H. H. The action of gamma aminobutyric acid upon cortical electrical activity in the cat. J Physiol. 1957 Oct 30;138(3):365–380. doi: 10.1113/jphysiol.1957.sp005856. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. KILLAM K. F., BAIN J. A. Convulsant hydrazides. I. In vitro and in vivo inhibition of vitamin B6 enzymes by convulsant hydrazides. J Pharmacol Exp Ther. 1957 Feb;119(2):255–262. [PubMed] [Google Scholar]
  15. KILLAM K. F. Convulsant hydrazides. II. Comparison of electrical changes and enzyme inhibition induced by the administration of thiosemicarbazide. J Pharmacol Exp Ther. 1957 Feb;119(2):263–271. [PubMed] [Google Scholar]
  16. KNAUFF H. G. The free amino-acids of the cerebrospinal fluid. Nature. 1958 Oct 4;182(4640):937–937. doi: 10.1038/182937a0. [DOI] [PubMed] [Google Scholar]
  17. LOGOTHETIS J. Free amino acid content of cerebrospinal fluid in humans and dogs. Neurology. 1958 Apr;8(4):299–302. doi: 10.1212/wnl.8.4.299. [DOI] [PubMed] [Google Scholar]
  18. McLENNAN H. A comparison of some physiological properties of an inhibitory factor from brain (factor I) and of gamma-aminobutyric acid and related compounds. J Physiol. 1957 Nov 14;139(1):79–86. doi: 10.1113/jphysiol.1957.sp005876. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. McLENNAN H. The identification of one active component from brain extracts containing factor I. J Physiol. 1959 May 19;146(2):358–368. doi: 10.1113/jphysiol.1959.sp006197. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. PURPURA D. P., GIRADO M., GRUNDFEST H. Selective blockade of excitatory synapses in the cat brain by gamma-aminobutyric acid. Science. 1957 Jun 14;125(3259):1200–1202. doi: 10.1126/science.125.3259.1200-a. [DOI] [PubMed] [Google Scholar]
  21. ROBERTS E., ROTHSTEIN M., BAXTER C. F. Some metabolic studies of gamma-aminobutyric acid. Proc Soc Exp Biol Med. 1958 Apr;97(4):796–802. doi: 10.3181/00379727-97-23883. [DOI] [PubMed] [Google Scholar]
  22. SJOERDSMA A., GILLESPIE L., UDENFRIEND S. A method for measurement of monoamine oxidase inhibition in man: application to studies on hypertension. Ann N Y Acad Sci. 1959 Sep 17;80:969–980. doi: 10.1111/j.1749-6632.1959.tb49272.x. [DOI] [PubMed] [Google Scholar]
  23. TABACHNICK I. I., RUBIN A. A. Some relationships between peripheral monoamine oxidase inhibition and brain 5-hydroxytryptamine levels in rats. Proc Soc Exp Biol Med. 1959 Jul;101(3):435–437. doi: 10.3181/00379727-101-24969. [DOI] [PubMed] [Google Scholar]
  24. TEDESCHI R. E., TEDESCHI D. H., AMES P. L., COOK L., MATTIS P. A., FELLOWS E. J. Some pharmacological observations on tranylcypromine (SKF trans-385), a potent inhibitor of monoamine oxidase. Proc Soc Exp Biol Med. 1959 Nov;102:380–381. doi: 10.3181/00379727-102-25256. [DOI] [PubMed] [Google Scholar]
  25. WALASZEK E., ABOOD L. G. Fixation of 5-hydroxytryptamine by brain mitochondria. Proc Soc Exp Biol Med. 1959 May;101(1):37–40. doi: 10.3181/00379727-101-24824. [DOI] [PubMed] [Google Scholar]

Articles from The Journal of Physiology are provided here courtesy of The Physiological Society

RESOURCES