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. 2006 Feb 4;332(7536):304. doi: 10.1136/bmj.332.7536.304

Pulmonary embolism in hospital practice

Certain crucial procedures were omitted

Adrian J B Brady 1
PMCID: PMC1360413  PMID: 16455743

Editor—Robinson says that diagnosis of pulmonary embolism can be difficult but does not mention the available scoring systems that are useful in defining the likelihood of pulmonary thromboembolism.1,2 Most importantly, she makes no mention of biomarkers and does not emphasise the critical importance of echocardiography or computed tomography scanning to identify right ventricular strain.

Figure 1.

Figure 1

Patients with a raised troponin concentration (I or T) and echo or computed tomographic evidence of right ventricular overload have 10 times the risk of death or major adverse event than individuals with a normal troponin value and normal right ventricular function.3,4

Importantly, the recommendation of low molecular weight heparin as initial treatment for all applies only to stable patients. Patients with shock should receive intravenous heparin, since cutaneous perfusion is compromised, and low molecular weight heparin may not be absorbed.

Finally, Robinson makes no mention of life saving surgical embolectomy or percutaneous fragmentation procedures, which have a key role in a gravely ill patients with massive pulmonary embolism.2,5

Modern management of patients with pulmonary embolism demands three investigations: an immediate troponin measurement, computed tomographic pulmonary angiography, and definition of involvement of the right ventricle by computed tomography or echocardiography. Without these we will remain stuck in 1990s medicine.

Competing interests: AJBB is the UK representative, European Society of Cardiology Pulmonary Embolism Committee. He is also a member of the steering committee, International Trial of Thrombolysis in Pulmonary Embolism.

References

  • 1.Robinson GV. Pulmonary embolism in hospital practice. BMJ 2006;332: 156-60. (21 January.) [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 2.Task Force on Pulmonary Embolism. Guidelines on diagnosis and management of acute pulmonary embolism. Eur Heart J 2000;21: 1301-36. [DOI] [PubMed] [Google Scholar]
  • 3.Kucher N, Wallmann D, Carone A, Windecker S, Meier B, Hess OM. Incremental prognostic value of troponin I and echocardiography in patients with acute pulmonary embolism. Eur Heart J 2003;24: 1651-6. [DOI] [PubMed] [Google Scholar]
  • 4.Konstantinides S, Geibel A, Olschewski M, Kasper W, Hruska N, Jackle S, et al. Importance of cardiac troponins I and T in risk stratification of patients with acute pulmonary embolism. Circulation 2002;106: 1263-8. [DOI] [PubMed] [Google Scholar]
  • 5.Brady AJB, Crake T, Oakley CM. Percutanous fragmentation and distal dispersion of proximal pulmonary embolus. Lancet 1991;338: 1186-9. [DOI] [PubMed] [Google Scholar]

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